Overview

  • Product name

  • Description

    Rabbit polyclonal to DUSP10
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human DUSP10 (internal sequence). The exact sequence is proprietary.
    Database link: Q9Y6W6

  • Positive control

    • IHC-P: U87 xenograft tissue. WB: HeLa and HCT 116 whole cell lysate. ICC/IF: HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab228987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dual specificity phosphatase 10 antibody
    • Dual specificity phosphatase MKP 5 antibody
    • Dual specificity phosphatase MKP5 antibody
    • Dual specificity protein phosphatase 10 antibody
    • DUS10_HUMAN antibody
    • DUSP 10 antibody
    • DUSP10 antibody
    • DUSP10 protein antibody
    • MAP kinase phosphatase 5 antibody
    • Mitogen activated protein kinase phosphatase 5 antibody
    • Mitogen-activated protein kinase phosphatase 5 antibody
    • MKP 5 antibody
    • MKP-5 antibody
    • MKP5 antibody
    • Serine/threonine specific protein phosphatase antibody
    see all

Images

  • All lanes : Anti-DUSP10 antibody (ab228987) at 1/1000 dilution

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 2 : HCT 116 (human colorectal carcinoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 53 kDa



    10% SDS-PAGE

  • HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for DUSP10 (green) using ab228987 (1/200 dilution) in ICC/IF. Cells were fixed in paraformaldehyde. Counterstain: Hoechst 33342 (blue).

  • Paraffin-embedded U87 xenograft tissue stained for DUSP10 with ab228987 at 1/100 dilution in immunohistochemical analysis.

References

ab228987 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228987.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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