Overview

  • Product name

  • Description

    Rabbit polyclonal to DUSP23
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human DUSP23 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control

    • Human brain cerebellum.

Properties

Applications

Our Abpromise guarantee covers the use of ab61566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function

    Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
  • Tissue specificity

    Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm > cytosol. Nucleus. Mainly cytosolic. Also nuclear.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dual specificity phosphatase 23 antibody
    • Dual specificity protein phosphatase 23 antibody
    • DUS23_HUMAN antibody
    • Dusp23 antibody
    • DUSP25 antibody
    • EC 3.1.3.16 antibody
    • EC 3.1.3.48 antibody
    • FLJ20442 antibody
    • LDP 3 antibody
    • LDP-3 antibody
    • LDP3 antibody
    • Low molecular mass dual specificity phosphatase 3 antibody
    • MOSP antibody
    • RP11-190A12.1 antibody
    • VH1 like member Z antibody
    • VH1 like phosphatase Z antibody
    • VH1-like phosphatase Z antibody
    • VHZ antibody
    see all

Images

  • ab61566 at 10µg/ml staining DUSP23 in human brain cerebellum by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

References

ab61566 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Mouse Tissue sections (Lung)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: 10mM Citric Acid, 0.05% Tween 20, pH 6.0
Permeabilization
No
Specification
Lung
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Fixative
Formalin

Abcam user community

Verified customer

Submitted Sep 22 2015

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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