Overview

  • Product name

  • Description

    Rabbit polyclonal to DUSP2/PAC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide corresponding to Human DUSP2/PAC1 aa 251-314 (C terminal).

  • Positive control

    • HeLa cell lysate
      Paraformaldehyde fixed HeLa cells
      Oral CA tissue
  • General notes

    Keep as concentrated solution.

     This product was previously labelled as DUSP2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab137640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Suggested antigen retrieval using heat mediated 10mM citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).
ICC/IF 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 34 kDa.

Target

  • Function

    Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
  • Tissue specificity

    Expressed in hematopoietic tissues.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dual specificity phosphatase 2 antibody
    • Dual specificity protein phosphatase 2 antibody
    • Dual specificity protein phosphatase PAC 1 antibody
    • Dual specificity protein phosphatase PAC-1 antibody
    • DUS2_HUMAN antibody
    • DUSP 2 antibody
    • DUSP2 antibody
    • PAC 1 antibody
    • PAC1 antibody
    • Serine/threonine specific protein phosphatase antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Oral CA tissue, labelling DUSP2/PAC1 with ab137640 at 1/100 dilution.

  • Anti-DUSP2/PAC1 antibody (ab137640) at 1/100 dilution + Hela whole cell lysate at 30 µg

    Predicted band size: 34 kDa



    10% SDS PAGE
  • Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, labelling DUSP2/PAC1 with ab137640 at 1/1000 dilution (left), costained with Hoechst 33342 (right).

References

This product has been referenced in:

See 1 Publication for this product

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