Key features and details
- Rabbit polyclonal to DUSP7
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DUSP7 antibody
See all DUSP7 primary antibodies
DescriptionRabbit polyclonal to DUSP7
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide with a sequence corresponding to a region within amino acids 258 and 320 of Human DUSP7 (NP_001938)
- 293T, H1299, HepG2, Molt-4 and Raji cell lines.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab95960 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 41 kDa.|
|IHC-P||1/100 - 1/500.|
|ICC/IF||1/100 - 1/200.|
FunctionRegulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors.
Tissue specificityExpressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells.
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain.
- Information by UniProt
- Dual specificity phosphatase 7 antibody
- Dual specificity protein phosphatase 7 antibody
- Dual specificity protein phosphatase PYST2 antibody
Anti-DUSP7 antibody (ab95960) at 1/1000 dilution + Raji whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE
ab95960, at 1/200, staining paraformaldehyde-fixed A549 cells by Immunofluorescence. Lower image merged with DNA probe.
ab95960, at 1/100, staining paraffin-embedded NCIN87 xenograft, by Immunohistochemistry.
ab95960 has been referenced in 2 publications.
- Wu L et al. Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1. Free Radic Biol Med 153:140-158 (2020). PubMed: 32311490
- Yang W et al. Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis. Cancer Manag Res 12:2327-2337 (2020). PubMed: 32273769