Overview

  • Product name

  • Description

    Rabbit polyclonal to DUSP8
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment within Human DUSP8 aa 1-372. The exact sequence is proprietary.
    Database link: Q13202

  • Positive control

    • Jurkat and Raji whole cell lysates; RD cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab184134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    This protein shows both activity toward tyrosine-protein phosphate as well as with serine/threonine-protein phosphate.
  • Tissue specificity

    Abundant in brain, heart and skeletal muscle.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • C11orf81 antibody
    • Chromosome 11 open reading frame 81 antibody
    • Deubiquitinating enzyme 8 antibody
    • Dual Specificity Phosphatase 8 antibody
    • Dual specificity phosphatase M3/6 antibody
    • Dual specificity protein phosphatase 8 antibody
    • Dual specificity protein phosphatase hVH 5 antibody
    • Dual specificity protein phosphatase hVH-5 antibody
    • DUS8 antibody
    • DUS8_HUMAN antibody
    • DUSP8 antibody
    • EC 3.1.3.16 antibody
    • EC 3.1.3.48 antibody
    • FLJ42476 antibody
    • FLJ42958 antibody
    • H1 phosphatase vaccinia virus homolog antibody
    • H1 phosphatase, vaccinia virus, homolog of antibody
    • HB5 antibody
    • hUBPy antibody
    • HVH5 antibody
    • HVH8 antibody
    • M3/6, mouse, homolog of antibody
    • Neuronal tyrosine threonine phosphatase 1 antibody
    • Serine/threonine specific protein phosphatase antibody
    • Ubiquitin carboxyl terminal hydrolase 8 antibody
    • Ubiquitin specific processing protease 8 antibody
    • Ubiquitin thiolesterase 8 antibody
    • VH5 antibody
    see all

Images

  • All lanes : Anti-DUSP8 antibody (ab184134) at 1/3000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate

    Predicted band size: 66 kDa



    7.5 % SDS-PAGE

  • Immunofluorescent analysis of methanol fixed RD cells labeling DUSP8 using ab184134 at 1/500 dilution. Right image costained with Hoechst 33342.

References

This product has been referenced in:

  • Liu R  et al. DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling. Circ Res 119:249-60 (2016). WB ; Mouse . Read more (PubMed: 27225478) »
See 1 Publication for this product

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