Anti-DYNC1H1 antibody (ab223060)
Key features and details
- Rabbit polyclonal to DYNC1H1
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DYNC1H1 antibody
See all DYNC1H1 primary antibodies -
Description
Rabbit polyclonal to DYNC1H1 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment corresponding to Human DYNC1H1 aa 1-100.
Database link: Q14204 -
Positive control
- IHC-P: Human testis tissue. ICC/IF: MCF7 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purity >95% -
Clonality
Polyclonal -
Isotype
IgG
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab223060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
1/50 - 1/200.
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IHC-P |
1/20 - 1/200.
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Notes |
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ICC/IF
1/50 - 1/200. |
IHC-P
1/20 - 1/200. |
Target
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Relevance
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. DYNC1H1 is a member of the cytoplasmic dynein heavy chain family which serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. -
Cellular localization
Cytoplasmic, Golgi Apparatus, Microtubule. -
Database links
- Entrez Gene: 1778 Human
- Entrez Gene: 13424 Mouse
- Entrez Gene: 29489 Rat
- Omim: 600112 Human
- SwissProt: Q14204 Human
- SwissProt: Q9JHU4 Mouse
- SwissProt: P38650 Rat
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Alternative names
- cytoplasmic dynein 1 heavy chain 1 antibody
- cytoplasmic dynein heavy chain 1 antibody
- DHC1 antibody
see all
Images
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Paraffin embedded human testis tissue stained for DYNC1H1 with ab223060 at 1/100 dilution in immunohistochemical analysis.
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MCF7 (human breast adenocarcinoma cell line) cells stained for DYNC1H1 (green) using ab223060 at 1/100 dilution in ICC/IF. Secondary: Alexa Fluor® 488-conjugated Goat Anti-Rabbit IgG (H+L).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab223060 has not yet been referenced specifically in any publications.