Overview

  • Product name

  • Description

    Rabbit polyclonal to DYNC1H1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human DYNC1H1 aa 12-66.
    Sequence:

    GSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSA LEQMR


    Database link: Q14204

  • Positive control

    • IHC-P: Human testis tissue. ICC/IF: MCF7 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab223060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/20 - 1/200.

Target

  • Relevance

    Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. DYNC1H1 is a member of the cytoplasmic dynein heavy chain family which serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits.
  • Cellular localization

    Cytoplasmic, Golgi Apparatus, Microtubule.
  • Database links

  • Alternative names

    • cytoplasmic dynein 1 heavy chain 1 antibody
    • cytoplasmic dynein heavy chain 1 antibody
    • DHC1 antibody
    • DHC1a antibody
    • DKFZp686P2245 antibody
    • DNCH1 antibody
    • Dnchc1 antibody
    • DNECL antibody
    • DYHC antibody
    • dynein heavy chain, cytosolic antibody
    • dynein, cytoplasmic 1, heavy chain 1 antibody
    • dynein, cytoplasmic-like antibody
    • HL-3 antibody
    • KIAA0325 antibody
    • p22 antibody
    see all

Images

  • Paraffin embedded human testis tissue stained for DYNC1H1 with ab223060 at 1/100 dilution in immunohistochemical analysis.

  • MCF7 (human breast adenocarcinoma cell line) cells stained for DYNC1H1 (green) using ab223060 at 1/100 dilution in ICC/IF. Secondary: Alexa Fluor® 488-conjugated Goat Anti-Rabbit IgG (H+L).

References

ab223060 has not yet been referenced specifically in any publications.

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