Product nameAnti-DYNC1LI2/LIC2 antibody [EPR11230(2)]
See all DYNC1LI2/LIC2 primary antibodies
DescriptionRabbit monoclonal [EPR11230(2)] to DYNC1LI2/LIC2
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
Species reactivityReacts with: Human
Recombinant fragment within Human DYNC1LI2/LIC2. The exact sequence is proprietary.
Database link: O43237
- Human fetal brain, NCI-H460 and SK-OV-3 lysates.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as DYNC1LI2
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab178702 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Predicted molecular weight: 54 kDa.|
FunctionActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Sequence similaritiesBelongs to the dynein light intermediate chain family.
Cellular localizationCytoplasm > cytoskeleton.
- Information by UniProt
- Cytoplasmic dynein 1 light intermediate chain 2 antibody
- cytosolic antibody
- DC1L2_HUMAN antibody
This product has been referenced in:
- Mahale SP et al. Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint. PLoS One 11:e0159646 (2016). WB ; Human . Read more (PubMed: 27441562) »
- Mahale S et al. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep 6:22 (2016). Read more (PubMed: 28003657) »