Anti-DYRK3 antibody (ab96617)
Key features and details
- Rabbit polyclonal to DYRK3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DYRK3 antibody -
Description
Rabbit polyclonal to DYRK3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 243 and 542 of DYRK3.
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Positive control
- Raji cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96617 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 66 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 66 kDa. |
Target
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Function
Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling. -
Tissue specificity
Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus. -
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Contains 1 protein kinase domain. -
Post-translational
modificationsAutophosphorylated on tyrosine residues. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 8444 Human
- Entrez Gene: 226419 Mouse
- Entrez Gene: 304775 Rat
- Omim: 603497 Human
- SwissProt: O43781 Human
- SwissProt: Q922Y0 Mouse
- SwissProt: Q4V8A3 Rat
- Unigene: 164267 Human
see all -
Alternative names
- Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
- Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
- Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab96617 has not yet been referenced specifically in any publications.