Product nameAnti-DYRK3 antibody [EPR6078(2)]
See all DYRK3 primary antibodies
DescriptionRabbit monoclonal [EPR6078(2)] to DYRK3
Tested applicationsSuitable for: WB, ICC/IFmore details
Unsuitable for: Flow Cyt,IHC-P or IP
Species reactivityReacts with: Human
Synthetic peptide, corresponding to residues within Human DYRK3 (UniProt: O43781).
- Jurkat, THP1 and HepG2 whole cell lysate (ab7900); HeLa cells.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab155949 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 66 kDa.|
|ICC/IF||1/100 - 1/250.|
FunctionNegative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
Tissue specificityIsoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Contains 1 protein kinase domain.
modificationsAutophosphorylated on tyrosine residues.
- Information by UniProt
- Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
- Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
- Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
All lanes : Anti-DYRK3 antibody [EPR6078(2)] (ab155949) at 1/1000 dilution
Lane 1 : Jurkat cell lysate
Lane 2 : THP1 cell lysate
Lane 3 : HeLa cell lysate
Lane 4 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 66 kDa
Immunofluorescent analysis of HepG2 cells, labeling DYRK3 with ab155949 at 1/100 dilution.
ab155949 has not yet been referenced specifically in any publications.