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I would like to know the epitope sequences of these antibodies.
Asked on Oct 12 2012
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ab7163 - Anti-Dystrophin antibody [MANDYS8]
This antibody Monoclonal Anti-Dystrophin, clone MANDYS8, recognizes an epitope located on the rod domain of the human dystrophin molecule, The publications that are cited in the data sheet, which mapped the epitope that the MANDYS8 clone recognises are:
1. Nguyen, thi Man, et al., FEBS Lett., 262, 237 (1990).
2. Sedgwick, S., et al. Rapid mapping by transposon mutagenesis of epitopes on the muscular dystrophy protein, dystrophin Nucl. Acids Res. (1991) 19(21): 5889-5894
According to these references the epitope recognised by this clone lies between residues 1400 and 1505.
Regarding the epitopes of the other 3 antibodies, ab3149, ab7164, ab15277 - no information is available regarding yet. As soon as we have further details, we will update the corresponding datasheets.
I hope that this helps and please do not hesitate to contact us if you require any further information or assistance.
Answered on Oct 12 2012