Anti-E Cadherin antibody (ab15148)

Rabbit polyclonal E Cadherin antibody. Validated in WB, IHC, ICC/IF and tested in Human, Pig. Cited in 93 publication(s). Independently reviewed in 13 review(s).

Publishing research using ab15148? Please let us know so that we can cite the reference in this datasheet.

ab15148 has been referenced in 108 publications.

  • Yang X & Meng T MicroRNA-431 affects trophoblast migration and invasion by targeting ZEB1 in preeclampsia. Gene 683:225-232 (2019). PubMed: 30315928
  • Gao J  et al. MicroRNA-590-5p functions as a tumor suppressor in breast cancer conferring inhibitory effects on cell migration, invasion, and epithelial-mesenchymal transition by downregulating the Wnt-ß-catenin signaling pathway. J Cell Physiol 234:1827-1841 (2019). PubMed: 30191949
  • Wang XH  et al. FGF represses metastasis of neuroblastoma regulated by MYCN and TGF-ß1 induced LMO1 via control of let-7 expression. Brain Res 1704:219-228 (2019). PubMed: 30321496
  • Villella VR  et al. A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease. EMBO J 38:N/A (2019). PubMed: 30498130
  • Pakula M  et al. The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells. Int J Mol Sci 20:N/A (2019). PubMed: 30609691
  • Liu DC  et al. Long noncoding RNA LEF1-AS1 silencing suppresses the initiation and development of prostate cancer by acting as a molecular sponge of miR-330-5p via LEF1 repression. J Cell Physiol N/A:N/A (2019). PubMed: 30613973
  • Shen B  et al. LncRNA MEG3 negatively modified osteosarcoma development through regulation of miR-361-5p and FoxM1. J Cell Physiol N/A:N/A (2019). PubMed: 30624782
  • Dai Y  et al. Ginsenoside Rg3 promotes the antitumor activity of gefitinib in lung cancer cell lines. Exp Ther Med 17:953-959 (2019). PubMed: 30651886
  • Xu YJ  et al. Epstein-Barr virus-coded miR-BART13 promotes nasopharyngeal carcinoma cell growth and metastasis via targeting of the NKIRAS2/NF-?B pathway. Cancer Lett 447:33-40 (2019). PubMed: 30684592
  • Ji S  et al. MicroRNA-372 functions as a tumor suppressor in cell invasion, migration and epithelial-mesenchymal transition by targeting ATAD2 in renal cell carcinoma. Oncol Lett 17:2400-2408 (2019). PubMed: 30719113
  • Lu C  et al. Coordination between TGF-ß cellular signaling and epigenetic regulation during epithelial to mesenchymal transition. Epigenetics Chromatin 12:11 (2019). PubMed: 30736855
  • Liu L  et al. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling. J Exp Clin Cancer Res 38:106 (2019). PubMed: 30819230
  • Zhang C  et al. CXCR4-Overexpressing Umbilical Cord Mesenchymal Stem Cells Enhance Protection against Radiation-Induced Lung Injury. Stem Cells Int 2019:2457082 (2019). PubMed: 30867667
  • Dong S  et al. HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3. J Exp Clin Cancer Res 38:110 (2019). PubMed: 30823895
  • Sun L  et al. Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression. BMC Cancer 19:247 (2019). PubMed: 30890138
  • Druzhkova I  et al. E-Cadherin in Colorectal Cancer: Relation to Chemosensitivity. Clin Colorectal Cancer 18:e74-e86 (2019). PubMed: 30415989
  • Ding Y  et al. Megakaryocytic leukemia 1 (MKL1) mediates high glucose induced epithelial-mesenchymal transition by activating LOX transcription. Biochem Biophys Res Commun 509:633-640 (2019). PubMed: 30553442
  • Zhou Q  et al. Uridine-cytidine kinase 2 promotes metastasis of hepatocellular carcinoma cells via the Stat3 pathway. Cancer Manag Res 10:6339-6355 (2018). PubMed: 30568496
  • Kim BG  et al. 3,3'-Diindolylmethane Suppressed Cyprodinil-Induced Epithelial-Mesenchymal Transition and Metastatic-Related Behaviors of Human Endometrial Ishikawa Cells via an Estrogen Receptor-Dependent Pathway. Int J Mol Sci 19:N/A (2018). PubMed: 29316692
  • Zhang L  et al. MicroRNA-124-3p directly targets PDCD6 to inhibit metastasis in breast cancer. Oncol Lett 15:984-990 (2018). PubMed: 29387242
  • Gao X  et al. miR-215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer. Int J Mol Med 42:1229-1236 (2018). PubMed: 29845221
  • Jiang G  et al. IL-17A and GDF15 are able to induce epithelial-mesenchymal transition of lung epithelial cells in response to cigarette smoke. Exp Ther Med 16:12-20 (2018). PubMed: 29977354
  • Kaowinn S  et al. STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2. Oncol Rep 40:2619-2627 (2018). PubMed: 30226605
  • Luo L  et al. MiR-124-3p suppresses glioma aggressiveness via targeting of Fra-2. Pathol Res Pract 214:1825-1834 (2018). PubMed: 30243808
  • Liu X  et al. ATP-binding cassette transporter A7 accelerates epithelial-to-mesenchymal transition in ovarian cancer cells by upregulating the transforming growth factor-ß signaling pathway. Oncol Lett 16:5868-5874 (2018). PubMed: 30333865
  • Das JK  et al. Nuclear Respiratory Factor 1 Acting as an Oncoprotein Drives Estrogen-Induced Breast Carcinogenesis. Cells 7:N/A (2018). PubMed: 30486409
  • Zhu Y  et al. Overexpression of microRNA-612 Restrains the Growth, Invasion, and Tumorigenesis of Melanoma Cells by Targeting Espin. Mol Cells 41:119-126 (2018). PubMed: 29385671
  • Gooskens SL  et al. TCF21 hypermethylation regulates renal tumor cell clonogenic proliferation and migration. Mol Oncol 12:166-179 (2018). WB ; Human . PubMed: 29080283
  • Yang XH & Guo F miR-3147 serves as an oncomiR in vulvar squamous cell cancer via Smad4 suppression. Mol Med Rep 17:6397-6404 (2018). PubMed: 29512734
  • Guo W  et al. Up-regulated deubiquitinase USP4 plays an oncogenic role in melanoma. J Cell Mol Med 22:2944-2954 (2018). PubMed: 29542252
  • Yang Q  et al. Metformin Enhances the Effect of Regorafenib and Inhibits Recurrence and Metastasis of Hepatic Carcinoma After Liver Resection via Regulating Expression of Hypoxia Inducible Factors 2a (HIF-2a) and 30 kDa HIV Tat-Interacting Protein (TIP30). Med Sci Monit 24:2225-2234 (2018). PubMed: 29654226
  • Zhong J  et al. Therapeutic role of meloxicam targeting secretory clusterin-mediated invasion in hepatocellular carcinoma cells. Oncol Lett 15:7191-7199 (2018). PubMed: 29731881
  • Li L  et al. Long non-coding RNA H19 regulates viability and metastasis, and is upregulated in retinoblastoma. Oncol Lett 15:8424-8432 (2018). PubMed: 29805578
  • Duan L  et al. VEGFC/VEGFR3 axis mediates TGFß1-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cells. PLoS One 13:e0200452 (2018). PubMed: 29995950
  • Lun W  et al. MiR-218 regulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF. Cancer Cell Int 18:83 (2018). PubMed: 29977158
  • Feng R  et al. Nab-paclitaxel interrupts cancer-stromal interaction through C-X-C motif chemokine 10-mediated interleukin-6 downregulation in vitro. Cancer Sci 109:2509-2519 (2018). PubMed: 29902349
  • Zhang Y  et al. Apigenin suppresses mouse peritoneal fibrosis by down-regulating miR34a expression. Biomed Pharmacother 106:373-380 (2018). PubMed: 29966983
  • Eley L  et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. Elife 7:N/A (2018). PubMed: 29956664
  • Li L  et al. MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial-mesenchymal transition of hepatocellular carcinoma. Cancer Cell Int 18:95 (2018). PubMed: 29989015
  • Zhang H  et al. Inhibition of the PI3K/Akt signaling pathway reverses sorafenib-derived chemo-resistance in hepatocellular carcinoma. Oncol Lett 15:9377-9384 (2018). PubMed: 29928334
  • Li Y  et al. Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control. JCI Insight 3:N/A (2018). PubMed: 29769449
  • Wu DM  et al. MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer. Int J Biochem Cell Biol 102:59-70 (2018). PubMed: 29953965
  • Yang Z  et al. Cholesterol inhibits hepatocellular carcinoma invasion and metastasis by promoting CD44 localization in lipid rafts. Cancer Lett 429:66-77 (2018). WB . PubMed: 29746928
  • Hugo HJ  et al. Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin. Breast Cancer Res 19:86 (2017). PubMed: 28750639
  • Ding X  et al. KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition. Oncol Lett 13:2281-2289 (2017). WB ; Human . PubMed: 28454392
  • Zheng L  et al. Baicalin ameliorates renal fibrosis via inhibition of transforming growth factor ß1 production and downstream signal transduction. Mol Med Rep 15:1702-1712 (2017). WB, IHC-P ; Rat . PubMed: 28260014
  • Wu Y  et al. Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways. Int J Mol Sci 18:N/A (2017). PubMed: 28448446
  • Yu L  et al. SOCS3 overexpression inhibits advanced glycation end product-induced EMT in proximal tubule epithelial cells. Exp Ther Med 13:3109-3115 (2017). PubMed: 28587386
  • Feng T  et al. Decrease in stathmin expression by arsenic trioxide inhibits the proliferation and invasion of osteosarcoma cells via the MAPK signal pathway. Oncol Lett 14:1333-1340 (2017). PubMed: 28789348
  • Takahashi T  et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med 214:1129-1151 (2017). PubMed: 28232470
  • Ouyang J  et al. The role of aplysia ras homolog I in colon cancer cell invasion and adhesion. Exp Ther Med 14:5193-5199 (2017). PubMed: 29201236
  • Roth M  et al. Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP. PLoS One 12:e0188010 (2017). PubMed: 29182620
  • Wen D  et al. Micellar Delivery of miR-34a Modulator Rubone and Paclitaxel in Resistant Prostate Cancer. Cancer Res 77:3244-3254 (2017). PubMed: 28428276
  • Zhang M  et al. MiR-381 inhibits migration and invasion in human gastric carcinoma through downregulatedting SOX4. Oncol Lett 14:3760-3766 (2017). PubMed: 28927144
  • Kim YH  et al. Senescent tumor cells lead the collective invasion in thyroid cancer. Nat Commun 8:15208 (2017). IHC . PubMed: 28489070
  • Sun L  et al. Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma. Cancer Sci 108:1338-1346 (2017). WB . PubMed: 28387999
  • Al-Amer O E-Cadherin and FGFR1 Expression in Mouse Osteoblastogenesis in Normoxic Cultures. Int J Biomed Sci 13:13-19 (2017). WB . PubMed: 28533732
  • Hoang TV  et al. Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity. Epigenetics 12:27-40 (2017). PubMed: 27824296
  • White LJ  et al. The impact of detergents on the tissue decellularization process: A ToF-SIMS study. Acta Biomater 50:207-219 (2017). PubMed: 27993639
  • Arora N  et al. A process engineering approach to increase organoid yield. Development 144:1128-1136 (2017). PubMed: 28174251
  • Chen D  et al. Targeting BMI1+ Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma. Cell Stem Cell 20:621-634.e6 (2017). PubMed: 28285905
  • Shi X  et al. Rho differentially regulates the Hippo pathway by modulating the interaction between Amot and Nf2 in the blastocyst. Development 144:3957-3967 (2017). PubMed: 28947533
  • Wang C  et al. miR-146a-5p mediates epithelial-mesenchymal transition of oesophageal squamous cell carcinoma via targeting Notch2. Br J Cancer 115:1548-1554 (2016). PubMed: 27832663
  • Clark AJ & Petty HR Protocol for Biomarker Ratio Imaging Microscopy with Specific Application to Ductal Carcinoma In situ of the Breast. Front Cell Dev Biol 4:120 (2016). PubMed: 27857940
  • Zhang Y  et al. GDF11 improves tubular regeneration after acute kidney injury in elderly mice. Sci Rep 6:34624 (2016). PubMed: 27703192
  • Feng S  et al. Proton pump inhibitor pantoprazole inhibits the proliferation, self-renewal and chemoresistance of gastric cancer stem cells via the EMT/ß-catenin pathways. Oncol Rep 36:3207-3214 (2016). PubMed: 27748935
  • Sengupta D  et al. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics 15:765-75 (2016). PubMed: 26621846
  • Bai L  et al. OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3ß/snail/E-cadherin signaling. Oncotarget 7:10402-13 (2016). IHC . PubMed: 26863455
  • You A  et al. Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models. J Hematol Oncol 9:20 (2016). WB ; Human . PubMed: 26957312
  • Fischer KD  et al. Vitamin D Supplementation Reduces Induction of Epithelial-Mesenchymal Transition in Allergen Sensitized and Challenged Mice. PLoS One 11:e0149180 (2016). IHC-P ; Mouse . PubMed: 26872336
  • Hwang PY  et al. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. Sci Rep 6:28038 (2016). ICC/IF . PubMed: 27292569
  • Gao K  et al. Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. Int J Mol Med N/A:N/A (2016). WB . PubMed: 27840941
  • Cui Y  et al. Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition and analysis of their phosphorylation signaling pathways. Oncotarget 7:34356-70 (2016). Human . PubMed: 27102302
  • Zhu L  et al. Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis. Oncogene 35:5388-5399 (2016). WB ; Human . PubMed: 27109105
  • Armakolas N  et al. Possible role of the Ec peptide of IGF-1Ec in cartilage repair. Mol Med Rep 14:3066-72 (2016). ICC/IF ; Human . PubMed: 27571686
  • Zhou W  et al. MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4. Oncotarget 7:74059-74073 (2016). WB ; Human . PubMed: 27677076
  • Zheng X  et al. High expression of lncRNA PVT1 promotes invasion by inducing epithelial-to-mesenchymal transition in esophageal cancer. Oncol Lett 12:2357-2362 (2016). WB ; Human . PubMed: 27698800
  • Huang C  et al. Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Mol Med Rep 14:2555-65 (2016). IHC . PubMed: 27484148
  • Chen H  et al. ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition. World J Surg Oncol 14:195 (2016). WB ; Human . PubMed: 27460906
  • Nguyen DG  et al. Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro. PLoS One 11:e0158674 (2016). PubMed: 27387377
  • Fan Y  et al. Increased expression of FERM domain-containing 4A protein is closely associated with the development of rectal cancer. Exp Ther Med 11:421-426 (2016). PubMed: 26893625
  • Clark AJ & Petty HR Identification of lesion subtypes in biopsies of ductal carcinoma in situ of the breast using biomarker ratio imaging microscopy. Sci Rep 6:27039 (2016). PubMed: 27247112
  • Zhang X  et al. LRIG1 inhibits hypoxia-induced vasculogenic mimicry formation via suppression of the EGFR/PI3K/AKT pathway and epithelial-to-mesenchymal transition in human glioma SHG-44 cells. Cell Stress Chaperones 20:631-41 (2015). WB . PubMed: 25860915
  • Nemeth Z  et al. Heme oxygenase-1 in macrophages controls prostate cancer progression. Oncotarget 6:33675-88 (2015). PubMed: 26418896
  • Li Y  et al. Autocrine motility factor promotes epithelial-mesenchymal transition in endometrial cancer via MAPK signaling pathway. Int J Oncol 47:1017-24 (2015). PubMed: 26201353
  • Wang W  et al. Up-regulation of Serum MiR-130b-3p Level is Associated with Renal Damage in Early Lupus Nephritis. Sci Rep 5:12644 (2015). PubMed: 26316103
  • ErLin S  et al. Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell 26:1947-56 (2015). Mouse . PubMed: 25717188
  • Dhar G  et al. Acid gradient across plasma membrane can drive phosphate bond synthesis in cancer cells: acidic tumor milieu as a potential energy source. PLoS One 10:e0124070 (2015). WB . PubMed: 25874623
  • Lund K  et al. Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLoS One 10:e0123684 (2015). WB . PubMed: 25860483
  • Xie B  et al. DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1. J Exp Clin Cancer Res 34:101 (2015). WB ; Human . PubMed: 26362312
  • Clements D  et al. Wild type mesenchymal cells contribute to the lung pathology of lymphangioleiomyomatosis. PLoS One 10:e0126025 (2015). IF ; Human . PubMed: 25978616
  • Li H  et al. Transcription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-ß1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells. Mol Med Rep 11:3259-68 (2015). WB, ICC/IF ; Human . PubMed: 25586417
  • Huang C  et al. Upregulation of H19 promotes invasion and induces epithelial-to-mesenchymal transition in esophageal cancer. Oncol Lett 10:291-296 (2015). WB ; Human . PubMed: 26171017
  • El-Hayek S & Clarke HJ Follicle-Stimulating Hormone Increases Gap Junctional Communication Between Somatic and Germ-Line Follicular Compartments During Murine Oogenesis. Biol Reprod 93:47 (2015). IHC-P ; Mouse . PubMed: 26063870
  • Kwon S  et al. Monoclonal antibody targeting of the cell surface molecule TM4SF5 inhibits the growth of hepatocellular carcinoma. Cancer Res 74:3844-56 (2014). PubMed: 24802189
  • Fischer KD & Agrawal DK Vitamin D regulating TGF-ß induced epithelial-mesenchymal transition. Respir Res 15:146 (2014). WB ; Human . PubMed: 25413472
  • Choi SY  et al. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol 24:1435-50 (2013). PubMed: 23766535
  • Bao W  et al. Upregulation of TrkB promotes epithelial-mesenchymal transition and anoikis resistance in endometrial carcinoma. PLoS One 8:e70616 (2013). Human . PubMed: 23936232
  • Al Dhaheri Y  et al. Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NF?B signaling and reduction of nitric oxide production. PLoS One 8:e68808 (2013). WB, ICC/IF . PubMed: 23874773
  • Berghoff AS  et al. Invasion patterns in brain metastases of solid cancers. Neuro Oncol N/A:N/A (2013). PubMed: 24084410
  • Yan HB  et al. Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription. Carcinogenesis N/A:N/A (2013). IHC ; Human . PubMed: 24293408
  • Chen SR  et al. Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration. BMC Biol 11:22 (2013). IHC . PubMed: 23497137
  • Walker KA  et al. Quantum dots for multiplexed detection and characterisation of prostate cancer cells using a scanning near-field optical microscope. PLoS One 7:e31592 (2012). WB . PubMed: 22347497
  • Luciani A  et al. Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ?F508 cystic fibrosis transmembrane conductance regulator. Autophagy 8:1657-72 (2012). WB . PubMed: 22874563
  • Butler TM  et al. Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line. Reprod Biol Endocrinol 7:51 (2009). ICC/IF ; Human . PubMed: 19463178
  • Hughes JN  et al. A novel role for gamma-secretase in the formation of primitive streak-like intermediates from ES cells in culture. Stem Cells 27:2941-51 (2009). PubMed: 19750540
  • Burke JM & Hong J Fate of E-cadherin in early RPE cultures: transient accumulation of truncated peptides at nonjunctional sites. Invest Ophthalmol Vis Sci 47:3635-43 (2006). PubMed: 16877438
  • Wang TW  et al. The effect of gelatin-chondroitin sulfate-hyaluronic acid skin substitute on wound healing in SCID mice. Biomaterials 27:5689-97 (2006). PubMed: 16908060

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