Overview

  • Product name

  • Description

    Rabbit polyclonal to E1B-AP5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human E1B-AP5 aa 50-100.
    Database link: NP_008971.2

  • Positive control

    • Human controls: Breast Carcinoma, Colon Carcinoma, Laryngeal Squamous Cell Carcinoma, Linitis Plastica Stomach Cancer, Non Small Cell Lung Cancer, Ovarian Carcinoma, Prostate Carcinoma, Skin Basal Cell Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma, Testicular Seminoma Mouse controls: Brain, Testis
  • General notes

    Previously labelled as HNRPUL1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab84774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate or tris-EDTA pH9.0 buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
    • Sequence similarities

      Contains 1 B30.2/SPRY domain.
      Contains 1 SAP domain.
    • Domain

      The RGG-box domain is methylated.
    • Post-translational
      modifications

      Methylated.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • Adenovirus early region 1B associated protein 5 antibody
      • Adenovirus early region 1B-associated protein 5 antibody
      • E130317O14Rik antibody
      • E1B 55 kDa associated protein 5 antibody
      • E1B AP5 antibody
      • E1B-55 kDa-associated protein 5 antibody
      • E1B-AP5 antibody
      • E1BAP5 antibody
      • fb53d10 antibody
      • fk45c03 antibody
      • FLJ12944 antibody
      • Heterogeneous nuclear ribonucleoprotein U-like protein 1 antibody
      • HNRL1_HUMAN antibody
      • Hnrnpul1 antibody
      • HNRPUL1 antibody
      • MGC36621 antibody
      • MGC78330 antibody
      • wu:fb53d10 antibody
      • wu:fk45c03 antibody
      • zgc:85971 antibody
      see all

    Images

    • Staining of E1B-AP5 by Immunohistochemistry on a formalin fixed, paraffin embedded section of human breast carcinoma using a 1/100 dilution of ab84774. Detection: Red fluorescent goat anti rabbit IgG highly cross adsorbed antibody used at a dilution of 1/100.

    • Staining of E1B-AP5 by Immunohistochemistry on a formalin fixed, paraffin embedded section of human breast carcinoma using a 1/100 dilution of ab84774. Detection: DAB staining

    • Staining of E1B-AP5 by Immunohistochemistry on a formalin fixed, paraffin embedded section of human ovarian carcinoma using a 1/500 dilution of ab84774. Detection: DAB staining

    • Staining of E1B-AP5 by Immunohistochemistry on a formalin fixed, paraffin embedded section of mouse testis using a 1/500 dilution of ab84774. Detection: DAB staining

    References

    ab84774 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab84774.
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