Key features and details
- Rabbit polyclonal to E2F5
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-E2F5 antibody
See all E2F5 primary antibodies
DescriptionRabbit polyclonal to E2F5
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human E2F5 aa 1-50 (N terminal). 50 amino acid range mapping within amino acids 1-50 ESF-5
- MCF7, NIH/3T3 cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab44996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 58 kDa.|
FunctionTranscriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation.
Sequence similaritiesBelongs to the E2F/DP family.
- Information by UniProt
- E2F 5 antibody
- E2F transcription factor 5 antibody
- E2F transcription factor 5 p130 binding antibody
ab44996 has been referenced in 3 publications.
- Sun F et al. MicroRNA-544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5. Oncol Lett 18:4203-4209 (2019). PubMed: 31579422
- Li SM et al. The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1. J Exp Clin Cancer Res 37:219 (2018). PubMed: 30185212
- Vuong L et al. Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina. Invest Ophthalmol Vis Sci 53:4821-31 (2012). PubMed: 22714890