Product nameEAAT1 peptide
See all EAAT1 proteins and peptides
Our Abpromise guarantee covers the use of ab127026 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-EAAT1 antibody (ab416)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Tissue specificityHighly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Involvement in diseaseDefects in SLC1A3 are the cause of episodic ataxia type 6 (EA6) [MIM:612656]. EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia.
Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily.
- Information by UniProt
ab127026 has not yet been referenced specifically in any publications.