Anti-EBNA2 antibody [PE2] (ab90543)
Key features and details
- Mouse monoclonal [PE2] to EBNA2
- Suitable for: WB, IP, IHC-Fr, ICC/IF
- Isotype: IgG1
Overview
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Product name
Anti-EBNA2 antibody [PE2]
See all EBNA2 primary antibodies -
Description
Mouse monoclonal [PE2] to EBNA2 -
Host species
Mouse -
Tested applications
Suitable for: WB, IP, IHC-Fr, ICC/IFmore details -
Species reactivity
Reacts with: Epstein-Barr virus -
Immunogen
Recombinant fusion protein against EBNA2.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A/G purified -
Clonality
Monoclonal -
Clone number
PE2 -
Myeloma
x63-Ag8.653 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab90543 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 53 kDa.
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IP |
Use at an assay dependent concentration.
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IHC-Fr |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 53 kDa. |
IP
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
Target
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Relevance
The Epstein-Barr Virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family and is one of the most common viruses in humans. EBNA2 is one of the few genes of Epstein-Barr virus which are necessary for immortalization of human primary B lymphocytes. The EBNA2 protein acts as a transcriptional activator of several viral and cellular genes. -
Cellular localization
Nuclear matrix of host cells -
Database links
- SwissProt: P12978 Epstein-Barr virus
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Alternative names
- EBNA2 antibody
- EBV antibody
- EBV nuclear antigen 2 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (34)
ab90543 has been referenced in 34 publications.
- Sidorov S et al. CD4 + T cells are found within endemic Burkitt lymphoma and modulate Burkitt lymphoma precursor cell viability and expression of pathogenically relevant Epstein-Barr virus genes. Cancer Immunol Immunother 71:1371-1392 (2022). PubMed: 34668039
- USCAP 2022 Abstracts: Hematopathology (851-976). Lab Invest 102:942-1088 (2022). PubMed: 35302080
- USCAP 2022 Abstracts: Hematopathology (851-976). Mod Pathol 35:1016-1162 (2022). PubMed: 35302093
- Zvejniece L et al. Expression of the Chemokine Receptor CCR1 in Burkitt Lymphoma Cell Lines Is Linked to the CD10-Negative Cell Phenotype and Co-Expression of the EBV Latent Genes EBNA2, LMP1, and LMP2. Int J Mol Sci 23:N/A (2022). PubMed: 35408790
- Caruso LB et al. The nuclear lamina binds the EBV genome during latency and regulates viral gene expression. PLoS Pathog 18:e1010400 (2022). PubMed: 35421198