• Product name

  • Description

    Chicken polyclonal to EBP1
  • Host species

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Immunogen corresponds to the full length protein (Human).


Associated products


Our Abpromise guarantee covers the use of ab37649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    WB: 1/2000. Detects a band of approximately 41 kDa (predicted molecular weight: 44 kDa). We recommend using about 2.5 ug of positive control protein in the colorimetric method, and about 10x less for ECL detection.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).
    • Tissue specificity

      Expressed in several cell lines tested, including primary and transformed cell lines.
    • Sequence similarities

      Belongs to the peptidase M24 family.
    • Post-translational

      Phosphorylated on serine and threonine residues. Phosphorylation is enhanced by HRG treatment. Basal phosphorylation is PKC-dependent and HRG-induced phosphorylation is predominantly PKC-independent.
    • Cellular localization

      Cytoplasm. Nucleus > nucleolus. Tranlocates to the nucleus upon treatment with HRG.
    • Information by UniProt
    • Database links

    • Alternative names

      • 38kDa antibody
      • AA672939 antibody
      • Cell cycle protein p38 2G4 homolog antibody
      • Cell cycle protein p38-2G4 homolog antibody
      • ErbB-3 binding protein 1 antibody
      • ErbB3 binding protein 1 antibody
      • ErbB3-binding protein 1 antibody
      • ErbB3-binding protein Ebp1 antibody
      • hG4 1 antibody
      • hG4-1 antibody
      • IRES-specific cellular trans-acting factor 45 kDa antibody
      • MGC81621 antibody
      • MGC94070 antibody
      • Mpp1 antibody
      • p38 2G4 antibody
      • Pa2g4 antibody
      • PA2G4_HUMAN antibody
      • Plfap antibody
      • Proliferation associated 2G4 antibody
      • Proliferation associated 2G4, 38-KD antibody
      • Proliferation-associated 2G4, 38kDa antibody
      • Proliferation-associated 2G4, a antibody
      • Proliferation-associated protein 1 antibody
      • Proliferation-associated protein 2G4 antibody
      • Protein p38-2G4 antibody
      • si:dz150i12.2 antibody
      • wu:fb19b11 antibody
      • wu:ft56d05 antibody
      • zgc:86732 antibody
      see all


    • Anti-EBP1 antibody (ab37649) at 1/2000 dilution + E coli derived fusion protein

      Goat anti IgY HRP at 1/1000 dilution

      Developed using the ECL technique.

      Predicted band size: 44 kDa
      Observed band size: 41 kDa
      why is the actual band size different from the predicted?

      The arrow next to the image points to the EBP1 recombinant protein.


    ab37649 has not yet been referenced specifically in any publications.

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