Overview

  • Product name
    Anti-EBV Induced Gene 2/EBI2 antibody
    See all EBV Induced Gene 2/EBI2 primary antibodies
  • Description
    Mouse polyclonal to EBV Induced Gene 2/EBI2
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant full length protein corresponding to Human EBV Induced Gene 2/EBI2 aa 1-361.
    Sequence:

    MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNL LALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIG DALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKG VCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGA CFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILII VVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQ MMIHSKSSNGK

  • Positive control
    • EBV Induced Gene 2 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab168744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa.

Target

  • Function
    Orphan receptor that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha.
  • Tissue specificity
    Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ebi 2 antibody
    • EBI2 antibody
    • EBV induced G protein coupled receptor 2 antibody
    • EBV-induced G-protein coupled receptor 2 antibody
    • ebv-induced gene 2 antibody
    • Epstein Barr virus induced gene 2 (lymphocyte specific G protein coupled receptor) antibody
    • Epstein Barr virus induced gene 2 antibody
    • epstein-barr virus induced gene 2 antibody
    • Epstein-Barr virus-induced G-protein coupled receptor 2 antibody
    • G protein-coupled receptor 183 antibody
    • G-protein coupled receptor 183 antibody
    • GP183_HUMAN antibody
    • gpr183 antibody
    • hEBI2 antibody
    • Lymphocyte specific G protein coupled receptor antibody
    see all

Images

  • All lanes : Anti-EBV Induced Gene 2/EBI2 antibody (ab168744) at 1 µg/ml

    Lane 1 : EBV Induced Gene 2 transfected 293T cell lysate (39.82 KDa)
    Lane 2 : Non-transfected 293T cell lysate

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugated secondary antibody at 1/2500 dilution

    Predicted band size: 41 kDa

References

This product has been referenced in:
  • Zhang P  et al. G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition. Cell Res 25:1093-107 (2015). Read more (PubMed: 26358189) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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