Overview

  • Product name

    Anti-EBV Latent Membrane Protein 1 antibody [D24-G]
    See all EBV Latent Membrane Protein 1 primary antibodies
  • Description

    Rabbit monoclonal [D24-G] to EBV Latent Membrane Protein 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Synthetic peptide derived from an internal region of EBV Latent Membrane Protein.

  • Epitope

    Antibody recognizes the epitope located between Asp293 - Asp312
  • Positive control

    • Human lymph node tissue; corresponding to Hodgkin’s lymphoma and EBV infectious mononucleosis.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 8.00
    Preservative: 0.05% Sodium azide
    Constituents: 0.32% Tris HCl, 2% BSA
  • Concentration information loading...
  • Purification notes

    This immunoglobulin is the product of one single B-cell line from the crude anti-peptide polyclonal anti-serum. This antibody is purified using a propriety technique and offers a completely post-translationally modified and properly glycosylated antibody. This offers increased stability.
  • Clonality

    Monoclonal
  • Clone number

    D24-G
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab136633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    EBV is a human herpesvirus that establishes a life-long persistence in the host. The virus infects the vast majority of the world's adult population and is well known for its association with a broad spectrum of benign and malignant diseases, including infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, and is causally associated with lymphoid and epithelial malignancies, including post-transplant lymphoproliferative disorders, Hodgkin's disease, anaplastic nasopharyngeal carcinoma and gastric carcinomas. Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signalling pathways and contributes to EBV-associated oncogenesis. LMP1 can be expressed in some states of EBV latency, and significant induction of full-length LMP1 is also observed frequently during virus reactivation into the lytic cycle. LMP1 is critical for EBV-infected cell activation, adhesion and survival, and is usually expressed in the malignant cells.
  • Alternative names

    • BNLF1 antibody
    • EBV antibody
    • Epstein Barr virus antibody
    • HHV4 antibody
    • Human Herpesvirus 4 antibody
    • Latent membrane protein 1 antibody
    • LMP1 antibody
    see all

Images

  • Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human lymph node tissue corresponding to Hodgkin’s lymphoma labelling EBV Latent Membrane Protein with ab136633 antibody at 1/100 dilution.
  • Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human lymph node tissue corresponding to EBV infectious mononucleosis labelling EBV Latent Membrane Protein with ab136633 antibody at 1/100 dilution.

References

ab136633 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

Vielen Dank für Ihre Antwort.

Leider muss ich Ihnen bestätigen, dass wir keinen Antikörper gegen die extrazelluläre Domäne in Produktion haben.

Ich werde diesen Vorschlag allerdings gerne weitergeben. Leider kann ich damit aber nicht garantieren, dass dieser Antikörper tatsächlich ins Programm aufgenommen wird.

Ich möchte Sie deshalb gerne darauf hinweisen, dass wir einen Service für Spezialanfertigungen von Antikörpern haben.

http://www.epitomics.com/services/

Bitte lassen Sie mich wissen, ob Sie interessiert sind. Ich werde Sie dann gerne an die zuständige Person weiterleiten.

Ich wünsche Ihnen ein Frohes Neues Jahr 2013 und verbleibe

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