Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)](https://www.abcam.com/ps/products/136/ab136633/Images/ab136633-151193-anti-ebv-latent-membrane-protein-1-antibody-d24-g-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)")
Key features and details
- Rabbit monoclonal [D24-G] to EBV Latent Membrane Protein 1
- Suitable for: IHC-P
- Isotype: IgG
Overview
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Product name
Anti-EBV Latent Membrane Protein 1 antibody [D24-G]
See all EBV Latent Membrane Protein 1 primary antibodies -
Description
Rabbit monoclonal [D24-G] to EBV Latent Membrane Protein 1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Other species -
Immunogen
Synthetic peptide derived from an internal region of EBV Latent Membrane Protein.
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Epitope
Antibody recognizes the epitope located between Asp293 - Asp312 -
Positive control
- Human lymph node tissue; corresponding to Hodgkin’s lymphoma and EBV infectious mononucleosis.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.32% Tris HCl, 2% BSA -
Concentration information loading... -
Purification notes
This immunoglobulin is the product of one single B-cell line from the crude anti-peptide polyclonal anti-serum. This antibody is purified using a propriety technique and offers a completely post-translationally modified and properly glycosylated antibody. This offers increased stability. -
Clonality
Monoclonal -
Clone number
D24-G -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab136633 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Relevance
EBV is a human herpesvirus that establishes a life-long persistence in the host. The virus infects the vast majority of the world's adult population and is well known for its association with a broad spectrum of benign and malignant diseases, including infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, and is causally associated with lymphoid and epithelial malignancies, including post-transplant lymphoproliferative disorders, Hodgkin's disease, anaplastic nasopharyngeal carcinoma and gastric carcinomas. Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signalling pathways and contributes to EBV-associated oncogenesis. LMP1 can be expressed in some states of EBV latency, and significant induction of full-length LMP1 is also observed frequently during virus reactivation into the lytic cycle. LMP1 is critical for EBV-infected cell activation, adhesion and survival, and is usually expressed in the malignant cells. -
Alternative names
- BNLF1 antibody
- EBV antibody
- Epstein Barr virus antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human lymph node tissue corresponding to Hodgkin’s lymphoma labelling EBV Latent Membrane Protein with ab136633 antibody at 1/100 dilution.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)](https://www.abcam.com/ps/products/136/ab136633/Images/ab136633-151192-anti-ebv-latent-membrane-protein-1-antibody-d24-g-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Latent Membrane Protein 1 antibody [D24-G] (ab136633)Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human lymph node tissue corresponding to EBV infectious mononucleosis labelling EBV Latent Membrane Protein with ab136633 antibody at 1/100 dilution.
References (0)
ab136633 has not yet been referenced specifically in any publications.
