Anti-EBV Nuclear Antigen/EBNA1 antibody (ab20870)

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Overview

  • Product name

    Anti-EBV Nuclear Antigen/EBNA1 antibody
    See all EBV Nuclear Antigen/EBNA1 primary antibodies

  • Description

    Goat polyclonal to EBV Nuclear Antigen/EBNA1

  • Host species

    Goat

  • Specificity

    Epstein-Barr nuclear antigen. Non reactive with human lymphoid cells. Functions in ELISA against various recombinant EBNA-1 preps.

  • Tested applications

    Suitable for: ELISA, ICC/IFmore details

  • Species reactivity

    Reacts with: Other species

  • Immunogen

    Recombinant full length protein corresponding to EBV Nuclear Antigen/EBNA1.

  • General notes

     This product was previously labelled as EBV Nuclear Antigen

     

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • Storage buffer

    pH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: 0.0268% PBS
  • Concentration information loading...

  • Purity

    Ion Exchange Chromatography

  • Purification notes

    >95% pure. Sodium sulfate precipitation & ion-exchange chromatography.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • Relevance

    Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.

  • Cellular localization

    Nuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.

  • Alternative names

    • EBNA1 antibody
    • EBV nuclear antigen 1 antibody
    • Epstein Barr nuclear antigen 1 antibody
    • Epstein Barr virus antibody
    • HHV4 antibody
    • Human Herpesvirus 4 antibody
    see all

References

ab20870 has not yet been referenced specifically in any publications.

Publishing research using ab20870? Please let us know so that we can cite the reference in this datasheet.

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