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    ebv-nuclear-antigenebna1-antibody-ab20870.pdf

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Microbiology Organism Virus DNA Virus double stranded DNA Virus EBNA
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Anti-EBV Nuclear Antigen/EBNA1 antibody (ab20870)

  • Datasheet
  • SDS
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Abpromise

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Key features and details

  • Goat polyclonal to EBV Nuclear Antigen/EBNA1
  • Suitable for: ELISA, ICC/IF
  • Isotype: IgG

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Recombinant EBV Nuclear Antigen/EBNA1 protein (ab138345)
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Overview

  • Product name

    Anti-EBV Nuclear Antigen/EBNA1 antibody
    See all EBV Nuclear Antigen/EBNA1 primary antibodies
  • Description

    Goat polyclonal to EBV Nuclear Antigen/EBNA1
  • Host species

    Goat
  • Specificity

    Epstein-Barr nuclear antigen. Non reactive with human lymphoid cells. Functions in ELISA against various recombinant EBNA-1 preps.
  • Tested applications

    Suitable for: ELISA, ICC/IFmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Recombinant full length protein corresponding to EBV Nuclear Antigen/EBNA1.

  • General notes

     This product was previously labelled as EBV Nuclear Antigen

     

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

    Learn more here.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 0.0268% PBS
  • Concentration information loading...
  • Purity

    Ion Exchange Chromatography
  • Purification notes

    >95% pure. Sodium sulfate precipitation & ion-exchange chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Microbiology
    • Organism
    • Virus
    • DNA Virus
    • double stranded DNA Virus
    • EBNA

Associated products

  • Compatible Secondaries

    • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
    • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
  • Isotype control

    • Goat IgG, polyclonal - Isotype Control (ab37373)
  • Recombinant Protein

    • Recombinant EBV Nuclear Antigen/EBNA1 protein (ab138345)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab20870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Use at an assay dependent dilution.
ICC/IF
Use at an assay dependent dilution.
Notes
ELISA
Use at an assay dependent dilution.
ICC/IF
Use at an assay dependent dilution.

Target

  • Relevance

    Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
  • Cellular localization

    Nuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.
  • Alternative names

    • EBNA1 antibody
    • EBV nuclear antigen 1 antibody
    • Epstein Barr nuclear antigen 1 antibody
    • Epstein Barr virus antibody
    • HHV4 antibody
    • Human Herpesvirus 4 antibody
    see all

Protocols

  • Immunocytochemistry & immunofluorescence protocols

Click here to view the general protocols

Datasheets and documents

  • SDS download

  • Datasheet download

    Download

References (0)

Publishing research using ab20870? Please let us know so that we can cite the reference in this datasheet.

ab20870 has not yet been referenced specifically in any publications.

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