Anti-EBV Nuclear Antigen/EBNA1 antibody (ab20870)
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Overview
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Product nameAnti-EBV Nuclear Antigen/EBNA1 antibody
See all EBV Nuclear Antigen/EBNA1 primary antibodies -
DescriptionGoat polyclonal to EBV Nuclear Antigen/EBNA1
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Host speciesGoat
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SpecificityEpstein-Barr nuclear antigen. Non reactive with human lymphoid cells. Functions in ELISA against various recombinant EBNA-1 preps.
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Tested applicationsSuitable for: ELISA, ICC/IFmore details
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Species reactivityReacts with: Other species
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Immunogen
Recombinant full length protein corresponding to EBV Nuclear Antigen/EBNA1.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading... -
PurityIon Exchange Chromatography
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Purification notes>95% pure. Sodium sulfate precipitation & ion-exchange chromatography.
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab20870 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | Use at an assay dependent dilution. | |
| ICC/IF | Use at an assay dependent dilution. |
Target
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RelevanceEpstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
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Cellular localizationNuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.
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Alternative names
- EBNA1 antibody
- EBV nuclear antigen 1 antibody
- Epstein Barr nuclear antigen 1 antibody
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References
ab20870 has not yet been referenced specifically in any publications.
