Overview

  • Product name

    Echinacoside, Caffeic acid glycoside
  • Description

    Caffeic acid glycoside. Antiapoptotic agent.
  • Biological description

    Caffeic acid (ab120862) glycoside. Antiapoptotic agent. Stimulates proliferation and inhibits apoptosis via upregulation of TGF-β1 expression. Shows antiapoptotic and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    82854-37-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
  • Molecular weight

    786.73
  • Molecular formula

    C35H46O20
  • PubChem identifier

    5281771
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(C(C(O4)CO)O)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Li X  et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol 49:993-1000 (2014). Read more (PubMed: 24797709) »
  • Yang X  et al. Efficacy and safety of echinacoside in a rat osteopenia model. Evid Based Complement Alternat Med 2013:926928 (2013). Read more (PubMed: 23573159) »
  • Jia Y  et al. Echinacoside stimulates cell proliferation and prevents cell apoptosis in intestinal epithelial MODE-K cells by up-regulation of transforming growth factor-ß1 expression. J Pharmacol Sci 118:99-108 (2012). Read more (PubMed: 22186624) »
  • Zhao Q  et al. Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease. Brain Res 1346:224-36 (2010). Read more (PubMed: 20478277) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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