Key features and details
- Rabbit polyclonal to EDEM2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-EDEM2 antibody
See all EDEM2 primary antibodies
DescriptionRabbit polyclonal to EDEM2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
- Human small intestine tissue; RT-4 and U-251 MG cell lysates; Human plasma.
This product was previously labelled as C20orf31
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab204173 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 65 kDa.|
FunctionInvolved in endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Tissue specificityExpressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle.
Sequence similaritiesBelongs to the glycosyl hydrolase 47 family.
Cellular localizationSecreted. Endoplasmic reticulum lumen.
- Information by UniProt
- bA4204.1 antibody
- C20orf31 antibody
- C20orf49 antibody
ab204173 has not yet been referenced specifically in any publications.