Key features and details
- Rabbit polyclonal to EDG6/S1PR4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-EDG6/S1PR4 antibody
See all EDG6/S1PR4 primary antibodies
DescriptionRabbit polyclonal to EDG6/S1PR4
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Hamster, Cow, Pig, Monkey, Gorilla
Synthetic peptide within Human EDG6/S1PR4 (intracellular). The exact sequence is proprietary. 20 amino acid peptide from 2nd cytoplasmic domain.
Database link: O95977
- Recombinant Human EDG6/S1PR4 protein (ab160145) can be used as a positive control in WB. Human lymph node and Human spleen tissue.
This product was previously labelled as EDG6
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab188984 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 9.6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionReceptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Tissue specificitySpecifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- EDG6 antibody
- Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6 antibody
- Endothelial differentiation G protein coupled receptor 6 antibody
ab188984 has been referenced in 1 publication.
- Palangi A et al. Differential expression of S1P receptor subtypes in human bladder transitional cell carcinoma. Clin Transl Oncol N/A:N/A (2019). PubMed: 30712233