Overview

  • Product name

  • Description

    Rabbit polyclonal to EDIL3/DEL1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to Human EDIL3/DEL1 aa 123-452.
    Database link: O43854

  • Positive control

    • Mouse brain lysate; Breast ca
  • General notes

    Previously labelled as EDIL3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab151308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 54 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
  • Sequence similarities

    Contains 3 EGF-like domains.
    Contains 2 F5/8 type C domains.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • DEL1 antibody
    • Developmental endothelial locus 1 antibody
    • Developmentally regulated endothelial cell locus 1 protein antibody
    • Developmentally-regulated endothelial cell locus 1 protein antibody
    • Edil3 antibody
    • EDIL3_HUMAN antibody
    • EGF like repeat and discoidin I like domain containing protein 3 antibody
    • EGF like repeats and discoidin I like domains 3 antibody
    • EGF like repeats and discoidin I like domains protein 3 antibody
    • EGF-like repeat and discoidin I-like domain-containing protein 3 antibody
    • Integrin binding protein DEL1 antibody
    • Integrin-binding protein DEL1 antibody
    see all

Images

  • Anti-EDIL3/DEL1 antibody (ab151308) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg

    Predicted band size: 54 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Breast cancer tissue labeling EDIL3/DEL1 with ab151308 antibody at 1/250 dilution.

References

This product has been referenced in:

  • Moon PG  et al. Identification of Developmental Endothelial Locus-1 on Circulating Extracellular Vesicles as a Novel Biomarker for Early Breast Cancer Detection. Clin Cancer Res 22:1757-66 (2016). Read more (PubMed: 26603257) »
  • Damhofer H  et al. Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma. Mol Oncol N/A:N/A (2013). Read more (PubMed: 23998958) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151308.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up