EdU, DNA synthesis monitoring probe (ab146186)
Key features and details
- DNA synthesis monitoring probe
- CAS Number: 61135-33-9
- Purity: > 98%
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
EdU, DNA synthesis monitoring probe -
Description
DNA synthesis monitoring probe -
Alternative names
- 2'-Deoxy-5-ethynyluridine
- 5-EdU
- 5-Ethynyl-2'-deoxyuridine
- EdU
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Purity
> 98% -
CAS Number
61135-33-9 -
Chemical structure
Properties
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Molecular weight
252.22 -
Molecular formula
C11H12N2O5 -
PubChem identifier
472172 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C#CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O -
Source
Synthetic
Images
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Chemical Structure - EdU, DNA synthesis monitoring probe (ab146186)2D chemical structure image of ab146186, EdU, DNA synthesis monitoring probe
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (13)
ab146186 has been referenced in 13 publications.
- Wu C et al. FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991. Evid Based Complement Alternat Med 2022:3945446 (2022). PubMed: 35280504
- Robinson DCL et al. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. Dev Cell 56:1014-1029.e7 (2021). PubMed: 33735618
- Zhuo M et al. Transient activation of tumoral DNA damage tolerance pathway coupled with immune checkpoint blockade exerts durable tumor regression in mouse melanoma. Pigment Cell Melanoma Res 34:605-617 (2021). PubMed: 33124186
- Tichy ED et al. Persistent NF-?B activation in muscle stem cells induces proliferation-independent telomere shortening. Cell Rep 35:109098 (2021). PubMed: 33979621
- Mitoyan L et al. A stem cell population at the anorectal junction maintains homeostasis and participates in tissue regeneration. Nat Commun 12:2761 (2021). PubMed: 33980830