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    edu-dna-synthesis-monitoring-probe-ab146186.pdf

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EdU, DNA synthesis monitoring probe (ab146186)

  • Datasheet
  • SDS
  • COA
Submit a review Submit a question References (13)

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Chemical Structure - EdU, DNA synthesis monitoring probe (ab146186)

    Key features and details

    • DNA synthesis monitoring probe
    • CAS Number: 61135-33-9
    • Purity: > 98%
    • Soluble in water to 10 mM and in DMSO to 100 mM
    • Form / State: Solid
    • Source: Synthetic

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    Overview

    • Product name

      EdU, DNA synthesis monitoring probe
    • Description

      DNA synthesis monitoring probe
    • Alternative names

      • 2'-Deoxy-5-ethynyluridine
      • 5-EdU
      • 5-Ethynyl-2'-deoxyuridine
      • EdU
    • Purity

      > 98%
    • CAS Number

      61135-33-9
    • Chemical structure

      Chemical Structure

    Properties

    • Molecular weight

      252.22
    • Molecular formula

      C11H12N2O5
    • PubChem identifier

      472172
    • Storage instructions

      Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in water to 10 mM and in DMSO to 100 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C#CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O
    • Source

      Synthetic

    Images

    • Chemical Structure - EdU, DNA synthesis monitoring probe (ab146186)
      Chemical Structure - EdU, DNA synthesis monitoring probe (ab146186)
      2D chemical structure image of ab146186, EdU, DNA synthesis monitoring probe

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (13)

    Publishing research using ab146186? Please let us know so that we can cite the reference in this datasheet.

    ab146186 has been referenced in 13 publications.

    • Wu C  et al. FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and Predicts Sensitivity to PD0332991. Evid Based Complement Alternat Med 2022:3945446 (2022). PubMed: 35280504
    • Robinson DCL  et al. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. Dev Cell 56:1014-1029.e7 (2021). PubMed: 33735618
    • Zhuo M  et al. Transient activation of tumoral DNA damage tolerance pathway coupled with immune checkpoint blockade exerts durable tumor regression in mouse melanoma. Pigment Cell Melanoma Res 34:605-617 (2021). PubMed: 33124186
    • Tichy ED  et al. Persistent NF-?B activation in muscle stem cells induces proliferation-independent telomere shortening. Cell Rep 35:109098 (2021). PubMed: 33979621
    • Mitoyan L  et al. A stem cell population at the anorectal junction maintains homeostasis and participates in tissue regeneration. Nat Commun 12:2761 (2021). PubMed: 33980830
    View all Publications for this product

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