Anti-EEA1 antibody [1G11] - Early Endosome Marker (ab70521)

Publishing research using ab70521? Please let us know so that we can cite the reference in this datasheet.

ab70521 has been referenced in 42 publications.

  • Autour A  et al. Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells. Nat Commun 9:656 (2018). PubMed: 29440634
  • Puri C  et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell 45:114-131.e8 (2018). WB, ICC/IF . PubMed: 29634932
  • Poulsen ET  et al. An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients. Front Mol Neurosci 10:59 (2017). ICC/IF . PubMed: 28360834
  • Zollo A  et al. Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele. Neural Plast 2017:1892612 (2017). ICC/IF ; Human . PubMed: 28634550
  • Chen X  et al. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci 8:129 (2016). IHC . PubMed: 27375475
  • Aizawa S  et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy 12:565-78 (2016). IF . PubMed: 27046251
  • Matrone C  et al. Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease. PLoS One 11:e0160501 (2016). PubMed: 27509067
  • Wu X  et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun 7:10533 (2016). ICC/IF ; Human . PubMed: 26837467
  • Torgersen ML  et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget 7:86871-86888 (2016). ICC/IF ; Human . PubMed: 27894086
  • Moreau K  et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun 6:8045 (2015). ICC/IF ; Human . PubMed: 26289944
  • Date K  et al. Pancreatic a-Amylase Controls Glucose Assimilation by Duodenal Retrieval through N-Glycan-specific Binding, Endocytosis, and Degradation. J Biol Chem 290:17439-50 (2015). PubMed: 26023238
  • Verma N  et al. PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition. Nat Commun 6:6064 (2015). PubMed: 25648557
  • Kurgonaite K  et al. Essential role of endocytosis for interleukin-4-receptor-mediated JAK/STAT signalling. J Cell Sci 128:3781-95 (2015). PubMed: 26306492
  • Heinonen MT  et al. Tubulin- and actin-associating GIMAP4 is required for IFN-? secretion during Th cell differentiation. Immunol Cell Biol 93:158-66 (2015). IF ; Human . PubMed: 25287446
  • Askautrud HA  et al. Global gene expression analysis reveals a link between NDRG1 and vesicle transport. PLoS One 9:e87268 (2014). ICC/IF ; Human . PubMed: 24498060
  • Li J  et al. Anti-inflammatory response following uptake of apoptotic bodies by meningothelial cells. J Neuroinflammation 11:35 (2014). ICC/IF ; Human . PubMed: 24565420
  • Zavodszky E  et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun 5:3828 (2014). ICC/IF ; Human . PubMed: 24819384
  • Choi S  et al. Globotriaosylceramide induces lysosomal degradation of endothelial KCa3.1 in fabry disease. Arterioscler Thromb Vasc Biol 34:81-9 (2014). PubMed: 24158513
  • Gallart-Palau X  et al. Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to a-motoneurons and altered during motoneuron diseases. FASEB J 28:3618-32 (2014). PubMed: 24803543
  • Leonhardt RM  et al. Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils. Mol Biol Cell : (2013). PubMed: 23389629
  • Boonyaratanakornkit J  et al. Alix serves as an adaptor that allows human parainfluenza virus type 1 to interact with the host cell ESCRT system. PLoS One 8:e59462 (2013). ICC/IF ; Human . PubMed: 23527201
  • Park SH  et al. Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic ß-cells. Proc Natl Acad Sci U S A 110:12673-8 (2013). PubMed: 23858470
  • Puri C  et al. Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell 154:1285-99 (2013). PubMed: 24034251
  • Patel PD  et al. Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol 9:677-84 (2013). ICC/IF . PubMed: 23995768
  • Yamada M  et al. Hepatitis B virus envelope L protein-derived bio-nanocapsules: mechanisms of cellular attachment and entry into human hepatic cells. J Control Release 160:322-9 (2012). ICC ; Human . PubMed: 22100387
  • Jabara HH  et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol 13:612-20 (2012). WB . PubMed: 22581261
  • Bround MJ  et al. Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice. Cardiovasc Res 96:372-80 (2012). WB ; Mouse . PubMed: 22869620
  • Sneh-Edri H & Stepensky D 'IntraCell' plugin for assessment of intracellular localization of nano-delivery systems and their targeting to the individual organelles. Biochem Biophys Res Commun 405:228-33 (2011). ICC/IF ; Human . PubMed: 21219848
  • Markowska AI  et al. Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol Chem 286:29913-21 (2011). ICC/IF ; Human . PubMed: 21715322
  • Rattner JB  et al. Primary cilia in fibroblast-like type B synoviocytes lie within a cilium pit: a site of endocytosis. Histol Histopathol 25:865-75 (2010). ICC/IF ; Human . PubMed: 20503175
  • Gu F  et al. Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A 105:2586-91 (2008). PubMed: 18272481
  • Ginger RS  et al. SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis. J Biol Chem 283:5486-95 (2008). PubMed: 18166528
  • Nassoury N  et al. The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic 8:718-32 (2007). PubMed: 17461796
  • Arnaud F  et al. Mechanisms of late restriction induced by an endogenous retrovirus. J Virol 81:11441-51 (2007). PubMed: 17699582
  • van Vliet SJ  et al. MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5. Eur J Immunol 37:2075-81 (2007). PubMed: 17616966
  • Savaskan NE  et al. Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma. Cell Mol Life Sci 64:230-43 (2007). PubMed: 17192809
  • Johnson MB  et al. Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway. Mol Biol Cell 18:743-54 (2007). PubMed: 17182845
  • Selak S  et al. Human autoantibodies against early endosome antigen-1 enhance excitatory synaptic transmission. Neuroscience 143:953-64 (2006). PubMed: 17113235
  • Ghosh M  et al. Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes. J Biol Chem 281:16615-24 (2006). PubMed: 16617059
  • Lu J  et al. The hereditary spastic paraplegia protein spartin localises to mitochondria. J Neurochem 98:1908-19 (2006). PubMed: 16945107
  • Selak S & Fritzler MJ Altered neurological function in mice immunized with early endosome antigen 1. BMC Neurosci 5:2 (2004). PubMed: 14728723
  • Selak S  et al. Early endosome antigen. 1: An autoantigen associated with neurological diseases. J Investig Med 47:311-8 (1999). PubMed: 10431486


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