Anti-EEA1 antibody - Early Endosome Marker (ab2900)

Knockout Tested Rabbit polyclonal EEA1 antibody. Validated in WB, IP, IHC, ICC, ICC/IF and tested in Mouse, Rat, Chicken, Hamster, Cow, Dog, Human, Xenopus laevis, Zebrafish, Rhesus monkey, Aplysia.

Publishing research using ab2900? Please let us know so that we can cite the reference in this datasheet.

ab2900 has been referenced in 146 publications.

  • Hoffmann AC  et al. Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Sci Rep 9:544 (2019). PubMed: 30679445
  • Bachelot A  et al. A common African variant of human connexin 37 is associated with Caucasian primary ovarian insufficiency and has a deleterious effect in vitro. Int J Mol Med 41:640-648 (2018). PubMed: 29207017
  • Yu Y  et al. Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis. Cell Death Dis 9:313 (2018). PubMed: 29472548
  • Yeganeh B  et al. Autophagy activation is required for influenza A virus-induced apoptosis and replication. Biochim Biophys Acta 1865:364-378 (2018). PubMed: 29108912
  • Cox CM  et al. The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation. Cell Mol Gastroenterol Hepatol 5:145-156 (2018). PubMed: 29322087
  • Einfalt T  et al. Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment. Nat Commun 9:1127 (2018). PubMed: 29555899
  • Sun Y  et al. SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins. Sci Rep 8:5287 (2018). PubMed: 29588492
  • Sun Q  et al. PEGylated TiO2 nanoparticles mediated inhibition of cell migration via integrin beta 1. Sci Technol Adv Mater 19:271-281 (2018). PubMed: 29707067
  • Mathias S  et al. Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy. J Biotechnol 271:47-55 (2018). ICC . PubMed: 29477386
  • Zulauf KE  et al. The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation. PLoS Pathog 14:e1007011 (2018). PubMed: 29709019
  • Lim D  et al. The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages. Nat Commun 9:2091 (2018). PubMed: 29844422
  • Papadimitriou C  et al. 3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aß42-Induced Loss of Human Neural Stem Cell Plasticity. Dev Cell 46:85-101.e8 (2018). PubMed: 29974866
  • Shi M  et al. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nat Commun 9:4987 (2018). PubMed: 30478271
  • Mittal E  et al. Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response. MBio 9:N/A (2018). PubMed: 30482832
  • Veglia F  et al. Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer. Nat Commun 8:2122 (2017). PubMed: 29242535
  • To EE  et al. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy. Nat Commun 8:69 (2017). PubMed: 28701733
  • Trajkovic K  et al. Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway. J Neurosci 37:9000-9012 (2017). PubMed: 28821645
  • Tsuda S  et al. Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages. Sci Rep 7:12989 (2017). ICC/IF . PubMed: 29021582
  • Brosius Lutz A  et al. Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury. Proc Natl Acad Sci U S A 114:E8072-E8080 (2017). IHC . PubMed: 28874532
  • Bissig C  et al. PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes. Traffic 18:747-757 (2017). PubMed: 28857423
  • Pohar J  et al. Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9. Nat Commun 8:15363 (2017). PubMed: 28530246
  • Petersen W  et al. Sequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development. Mol Biol Cell 28:726-735 (2017). PubMed: 28122820
  • Kim SW  et al. Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells. Sci Rep 7:6454 (2017). PubMed: 28743942
  • Lee YK  et al. Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential. Int J Nanomedicine 12:5761-5779 (2017). PubMed: 28848352
  • Pinilla-Macua I  et al. EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo. Elife 6:N/A (2017). PubMed: 29268862
  • Ait-Bouziad N  et al. Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes. Nat Commun 8:1678 (2017). PubMed: 29162800
  • Pavelin J  et al. Cellular v-ATPase is required for virion assembly compartment formation in human cytomegalovirus infection. Open Biol 7:N/A (2017). PubMed: 29093211
  • Sindhwani A  et al. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication. PLoS Pathog 13:e1006700 (2017). PubMed: 29084291
  • Li RS  et al. Chiral nanoprobes for targeting and long-term imaging of the Golgi apparatus. Chem Sci 8:6829-6835 (2017). PubMed: 29147508
  • Shlyakhtina Y  et al. Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells. Cell Death Dis 8:e3025 (2017). PubMed: 29048428
  • Kim E  et al. TRAF4 promotes lung cancer aggressiveness by modulating tumor microenvironment in normal fibroblasts. Sci Rep 7:8923 (2017). PubMed: 28827764
  • Wang X  et al. Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma. PLoS Pathog 13:e1006580 (2017). PubMed: 28957431
  • Kleinecke S  et al. Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy. Elife 6:N/A (2017). IF ; Mouse . PubMed: 28470148
  • Verzeaux L  et al. Intrinsic dynamics study identifies two amino acids of TIMP-1 critical for its LRP-1-mediated endocytosis in neurons. Sci Rep 7:5375 (2017). ICC/IF ; Mouse . PubMed: 28710453
  • Chen Y  et al. Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins. Mol Biol Cell 27:1272-85 (2016). IF . PubMed: 26941331
  • Ortiz DA  et al. Protein-Protein Interactions Suggest Novel Activities of Human Cytomegalovirus Tegument Protein pUL103. J Virol 90:7798-810 (2016). WB, ICC/IF ; Human . PubMed: 27334581
  • Albert V  et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med 8:232-46 (2016). WB ; Mouse . PubMed: 26772600
  • Gelis L  et al. Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes. J Biol Chem 291:17772-86 (2016). PubMed: 27226631
  • Kaur I  et al. Activity-Dependent Palmitoylation Controls SynDIG1 Stability, Localization, and Function. J Neurosci 36:7562-8 (2016). PubMed: 27445135
  • Martinez H  et al. Spatial-Temporal Study of Rab1b Dynamics and Function at the ER-Golgi Interface. PLoS One 11:e0160838 (2016). PubMed: 27500526
  • Cañas MA  et al. Outer Membrane Vesicles from the Probiotic Escherichia coli Nissle 1917 and the Commensal ECOR12 Enter Intestinal Epithelial Cells via Clathrin-Dependent Endocytosis and Elicit Differential Effects on DNA Damage. PLoS One 11:e0160374 (2016). ICC/IF ; Human . PubMed: 27487076
  • Bround MJ  et al. Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase. J Biol Chem 291:23490-23505 (2016). PubMed: 27621312
  • Doherty CM  et al. Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity. J Biol Chem 291:22160-22172 (2016). PubMed: 27582494
  • Xiong L  et al. Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response. EBioMedicine 9:45-60 (2016). PubMed: 27333042
  • Bourseau-Guilmain E  et al. Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells. Nat Commun 7:11371 (2016). WB, IHC-Fr, ICC/IF . PubMed: 27094744
  • Raha AA  et al. Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model. J Alzheimers Dis N/A:N/A (2016). IHC ; Mouse . PubMed: 27662313
  • Hutten TJ  et al. CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses. J Immunol 197:2715-25 (2016). PubMed: 27566820
  • Chanduri M  et al. Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. Biochem J 473:3031-47 (2016). PubMed: 27474409
  • Sorrell SL  et al. Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis. Kidney Int 89:105-112 (2016). PubMed: 26398495
  • Bartuzi P  et al. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun 7:10961 (2016). PubMed: 26965651
  • Liu J  et al. ATP-containing vesicles in stria vascular marginal cell cytoplasms in neonatal rat cochlea are lysosomes. Sci Rep 6:20903 (2016). PubMed: 26864824
  • Corcelle-Termeau E  et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy 12:833-49 (2016). PubMed: 27070082
  • Wahl S  et al. The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses. J Neurosci 36:2473-93 (2016). PubMed: 26911694
  • Clifford RJ  et al. Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu? uptake system. J Cell Sci 129:1711-21 (2016). PubMed: 26945057
  • Seebacher NA  et al. Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter. J Biol Chem 291:3796-820 (2016). PubMed: 26601947
  • Truong A  et al. Dynamics of internalization and recycling of the prometastatic membrane type 4 matrix metalloproteinase (MT4-MMP) in breast cancer cells. FEBS J 283:704-22 (2016). PubMed: 26663028
  • Klinger SC  et al. Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells. FEBS J 283:2476-93 (2016). PubMed: 27192064
  • Aits S  et al. Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay. Autophagy 11:1408-24 (2015). PubMed: 26114578
  • Lo Cicero A  et al. Exosomes released by keratinocytes modulate melanocyte pigmentation. Nat Commun 6:7506 (2015). PubMed: 26103923
  • Camorani S  et al. Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells. Oncotarget 6:37570-87 (2015). PubMed: 26461476
  • Mrschtik M  et al. DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death Differ 22:1714-26 (2015). PubMed: 25929859
  • Santiago-Tirado FH  et al. A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome. PLoS Pathog 11:e1004908 (2015). PubMed: 25970403
  • Zhao J & Hedera P Strumpellin and Spartin, Hereditary Spastic Paraplegia Proteins, are Binding Partners. J Exp Neurosci 9:15-25 (2015). ICC . PubMed: 25987849
  • Zhao L  et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med 7:1179-97 (2015). IHC . PubMed: 26139610
  • Satoh K  et al. ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing. J Biol Chem 290:24152-65 (2015). PubMed: 26260791
  • Yeganeh B  et al. Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1. Am J Physiol Lung Cell Mol Physiol 308:L270-86 (2015). PubMed: 25361566
  • Jahic A  et al. The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet J Rare Dis 10:147 (2015). PubMed: 26572744
  • van der Kant R  et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. J Biol Chem 290:30280-90 (2015). PubMed: 26463206
  • Da Ros M  et al. Retromer vesicles interact with RNA granules in haploid male germ cells. Mol Cell Endocrinol 401:73-83 (2015). PubMed: 25486514
  • Zeineddine R  et al. SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Mol Neurodegener 10:57 (2015). Mouse . PubMed: 26520394
  • Zhou Y  et al. Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease. J Clin Invest 125:3178-92 (2015). PubMed: 26121745
  • Riley AM  et al. Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5. Chembiochem 15:57-67 (2014). PubMed: 24311195
  • Diner I  et al. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. J Biol Chem 289:35296-313 (2014). PubMed: 25355317
  • Li J  et al. SNX13 reduction mediates heart failure through degradative sorting of apoptosis repressor with caspase recruitment domain. Nat Commun 5:5177 (2014). PubMed: 25295779
  • Stack J  et al. TRAM is required for TLR2 endosomal signaling to type I IFN induction. J Immunol 193:6090-102 (2014). PubMed: 25385819
  • Allen SJ  et al. Binding of HSV-1 glycoprotein K (gK) to signal peptide peptidase (SPP) is required for virus infectivity. PLoS One 9:e85360 (2014). ICC/IF . PubMed: 24465545
  • Chen D  et al. Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA. PLoS One 9:e87281 (2014). ICC/IF ; Human . PubMed: 24489888
  • Fathinajafabadi A  et al. CERKL, a retinal disease gene, encodes an mRNA-binding protein that localizes in compact and untranslated mRNPs associated with microtubules. PLoS One 9:e87898 (2014). ICC/IF ; Human . PubMed: 24498393
  • Müller J  et al. O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function. PLoS One 9:e88571 (2014). ICC/IF ; Mouse . PubMed: 24533113
  • Jin RU & Mills JC RAB26 coordinates lysosome traffic and mitochondrial localization. J Cell Sci 127:1018-32 (2014). PubMed: 24413166
  • Taha MS  et al. Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin. PLoS One 9:e91465 (2014). ICC/IF ; Human . PubMed: 24658146
  • Greer AM  et al. Serum IgE clearance is facilitated by human FceRI internalization. J Clin Invest 124:1187-98 (2014). ICC/IF . PubMed: 24569373
  • Vermehren-Schmaedick A  et al. Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking. PLoS One 9:e95113 (2014). IHC ; Rat . PubMed: 24732948
  • Yermakova A  et al. Antibody-mediated inhibition of ricin toxin retrograde transport. MBio 5:e00995 (2014). ICC/IF ; African green monkey . PubMed: 24713323
  • Srivastava L  et al. Immunomodulatory glycan lacto-N-fucopentaose III requires clathrin-mediated endocytosis to induce alternative activation of antigen-presenting cells. Infect Immun 82:1891-903 (2014). PubMed: 24566617
  • Kawasaki N  et al. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol 193:1560-6 (2014). PubMed: 25000981
  • Ramakrishnan R  et al. Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. J Immunol 192:2920-31 (2014). ICC ; Mouse, Human . PubMed: 24554775
  • Olofsson A  et al. Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways. MBio 5:e00979-14 (2014). IF . PubMed: 24846379
  • Kozyreva VK  et al. NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner. Mol Cancer Res 12:681-93 (2014). PubMed: 24574519
  • Wu XA  et al. Intracellular fate of spherical nucleic acid nanoparticle conjugates. J Am Chem Soc 136:7726-33 (2014). PubMed: 24841494
  • Kelly C  et al. Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 304:L371-82 (2013). PubMed: 23316065
  • Choi CH  et al. Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates. Proc Natl Acad Sci U S A 110:7625-30 (2013). ICC/IF . PubMed: 23613589
  • Giudice J  et al. Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B. Cell Commun Signal 11:18 (2013). Human . PubMed: 23497114
  • Windhorst S  et al. Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation. Biochem J 450:115-25 (2013). PubMed: 23186306
  • Arany S  et al. Nanoparticle-mediated Gene Silencing Confers Radioprotection to Salivary Glands In Vivo. Mol Ther 21:1182-94 (2013). Mouse . PubMed: 23511246
  • Masuzawa A  et al. Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 304:H966-82 (2013). ICC/IF . PubMed: 23355340
  • Burg VK  et al. Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study. J Neurosci 33:16072-87 (2013). PubMed: 24107941
  • Caster AH & Kahn RA Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex. J Biol Chem 288:28567-80 (2013). ICC/IF ; Human . PubMed: 23965993
  • Wang H  et al. Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination. J Immunol 191:6010-21 (2013). PubMed: 24218449
  • Nakayama A  et al. Ephrin-B2 controls PDGFRß internalization and signaling. Genes Dev 27:2576-89 (2013). ICC/IF ; Mouse . PubMed: 24298057
  • Khundadze M  et al. A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system. PLoS Genet 9:e1003988 (2013). Mouse . PubMed: 24367272
  • Abramowski D  et al. Transgenic expression of intraneuronal Aß42 but not Aß40 leads to cellular Aß lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology. J Neurosci 32:1273-83 (2012). ICC/IF ; Mouse . PubMed: 22279212
  • Xu Y  et al. Epidermal Growth Factor-induced Vacuolar (H+)-ATPase Assembly: A ROLE IN SIGNALING VIA mTORC1 ACTIVATION. J Biol Chem 287:26409-22 (2012). ICC/IF . PubMed: 22689575
  • Cho KJ  et al. Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins. J Biol Chem 287:43573-84 (2012). PubMed: 23124205
  • Perrot G  et al. LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion. Mol Cell Biol 32:3293-307 (2012). PubMed: 22711991
  • Morén B  et al. EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Mol Biol Cell 23:1316-29 (2012). PubMed: 22323287
  • Youn JI  et al. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol 91:167-81 (2012). PubMed: 21954284
  • Das S & Pellett PE Spatial Relationships between Markers for Secretory and Endosomal Machinery in Human Cytomegalovirus-Infected Cells versus Those in Uninfected Cells. J Virol 85:5864-79 (2011). PubMed: 21471245
  • Grimm MO  et al. Docosahexaenoic Acid Reduces Amyloid {beta} Production via Multiple Pleiotropic Mechanisms. J Biol Chem 286:14028-39 (2011). WB ; Human . PubMed: 21324907
  • Giudice J  et al. Differential endocytosis and signaling dynamics of insulin receptor variants IR-A and IR-B. J Cell Sci 124:801-11 (2011). PubMed: 21303927
  • Iyengar S  et al. Functional analysis of KAP1 genomic recruitment. Mol Cell Biol 31:1833-47 (2011). ICC/IF ; Human . PubMed: 21343339
  • Ha SD  et al. Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasm. J Biol Chem 285:2120-9 (2010). WB ; Human . PubMed: 19858192
  • Joset A  et al. Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. J Cell Biol 188:271-85 (2010). ICC/IF ; Rat . PubMed: 20083601
  • Sengers BG  et al. Characterisation of human bone marrow stromal cell heterogeneity for skeletal regeneration strategies using a two-stage colony assay and computational modelling. Bone 46:496-503 (2010). PubMed: 19818885
  • Lee PW  et al. The characteristics, biodistribution, magnetic resonance imaging and biodegradability of superparamagnetic core-shell nanoparticles. Biomaterials 31:1316-24 (2010). PubMed: 19959224
  • Wang L  et al. Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift. Anesthesiology 113:541-51 (2010). PubMed: 20683255
  • Zwart W  et al. The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells. J Cell Sci 123:3817-27 (2010). PubMed: 20971706
  • Pawliczek T & Crump CM Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression. J Virol 83:11254-64 (2009). WB ; Human . PubMed: 19692479
  • Tsitoura E  et al. Infection with herpes simplex type 1-based amplicon vectors results in an IRF3/7-dependent, TLR-independent activation of the innate antiviral response in primary human fibroblasts. J Gen Virol 90:2209-20 (2009). PubMed: 19515829
  • Desko MM  et al. Effects of N-glycosylation on the activity and localization of GlcNAc-6-sulfotransferase 1. Glycobiology 19:1068-77 (2009). PubMed: 19571171
  • Demonbreun AR  et al. Myoferlin is required for insulin-like growth factor response and muscle growth. FASEB J : (2009). PubMed: 20008164
  • Jabbour M  et al. Discrete domains of MARCH1 mediate its localization, functional interactions, and posttranscriptional control of expression. J Immunol 183:6500-12 (2009). ICC/IF ; Mouse . PubMed: 19880452
  • García CC  et al. Characterization of Junín virus particles inactivated by a zinc finger-reactive compound. Virus Res 143:106-13 (2009). WB ; African green monkey . PubMed: 19463727
  • Langlois S  et al. Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Mol Biol Cell 19:912-28 (2008). WB ; Rat . PubMed: 18162583
  • Yamakawa Y  et al. Identification and functional characterization of a bovine orthologue to DC-SIGN. J Leukoc Biol 83:1396-403 (2008). PubMed: 18319290
  • Overmeyer JH  et al. Active ras triggers death in glioblastoma cells through hyperstimulation of macropinocytosis. Mol Cancer Res 6:965-77 (2008). PubMed: 18567800
  • Stadler K  et al. Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level. Am J Respir Cell Mol Biol 39:142-9 (2008). PubMed: 18314540
  • Young JS  et al. Tubulobulbar Complexes Are Intercellular Podosome-Like Structures That Internalize Intact Intercellular Junctions During Epithelial Remodeling Events in the Rat Testis. Biol Reprod : (2008). ICC/IF ; Mouse . PubMed: 18799754
  • Bergami M  et al. Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes. J Cell Biol 183:213-21 (2008). IHC-FoFr ; Rat . PubMed: 18852301
  • Han J  et al. Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network. J Cell Sci 121:2217-23 (2008). WB, ICC/IF ; Human . PubMed: 18544638
  • Philips JA  et al. ESCRT factors restrict mycobacterial growth. Proc Natl Acad Sci U S A 105:3070-3075 (2008). WB ; Mouse . PubMed: 18287038
  • Laifenfeld D  et al. Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis. J Neurosci 27:7141-53 (2007). ICC/IF, WB ; Mouse . PubMed: 17611268
  • Guo D  et al. Protein kinase C-epsilon coimmunoprecipitates with cytochrome oxidase subunit IV and is associated with improved cytochrome-c oxidase activity and cardioprotection. Am J Physiol Heart Circ Physiol 293:H2219-30 (2007). PubMed: 17660387
  • Winter D  et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol 179:4272-82 (2007). ICC/IF ; Human . PubMed: 17785868
  • Brough D & Rothwell NJ Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death. J Cell Sci 120:772-81 (2007). PubMed: 17284521
  • Bonaccorsi L  et al. Altered endocytosis of epidermal growth factor receptor in androgen receptor positive prostate cancer cell lines. J Mol Endocrinol 38:51-66 (2007). PubMed: 17242169
  • Lu C  et al. The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool. Traffic 8:1246-64 (2007). PubMed: 17605762
  • Pak Y  et al. Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination. J Cell Biol 175:631-45 (2006). PubMed: 17116753
  • Dal Molin F  et al. Cell entry and cAMP imaging of anthrax edema toxin. EMBO J 25:5405-13 (2006). PubMed: 17082768
  • Vagin O  et al. The role of the beta1 subunit of the Na,K-ATPase and its glycosylation in cell-cell adhesion. J Biol Chem 281:39573-87 (2006). PubMed: 17052981
  • Kalabis J  et al. Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium. J Biol Chem 281:6434-41 (2006). PubMed: 16410243
  • Mintern JD  et al. Viral interference with B7-1 costimulation: a new role for murine cytomegalovirus fc receptor-1. J Immunol 177:8422-31 (2006). ICC/IF ; Chinese hamster . PubMed: 17142739
  • Flasza M  et al. Regulation of the nuclear localization of the human Nedd4-related WWP1 protein by Notch. Mol Membr Biol 23:269-76 (2006). PubMed: 16785210
  • Stenmark H  et al. Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger. J Biol Chem 271:24048-54 (1996). PubMed: 8798641
  • Mu FT  et al. EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif. J Biol Chem 270:13503-11 (1995). PubMed: 7768953
  • Mant A  et al. Acid sensitive background potassium channels K2P3.1 and K2P9.1 undergo rapid dynamin-dependent endocytosis. Channels (Austin) 7:288-302 (0). PubMed: 23807092

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