Key features and details
- Rabbit polyclonal to EFHD2/SWS1
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-EFHD2/SWS1 antibody
See all EFHD2/SWS1 primary antibodies
DescriptionRabbit polyclonal to EFHD2/SWS1
Specificityab106667 is predicted to not cross-react with EFHD1.
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human EFHD2/SWS1 (N terminal).
Database link: NP_077305
- Mouse brain tissue lysate and Human brain tissue.
Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.|
FunctionMay regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Tissue specificityFound in lymphocytes; preferentially expressed in CD8+ cells.
Sequence similaritiesContains 2 EF-hand domains.
Cellular localizationMembrane raft. In immature B-cell line WEHI231.
- Information by UniProt
- EF hand domain containing protein 2 antibody
- EF hand domain family, member D2 antibody
- EF-hand domain-containing protein D2 antibody
Lane 1 : Anti-EFHD2/SWS1 antibody (ab106667) at 1 µg/ml
Lane 2 : Anti-EFHD2/SWS1 antibody (ab106667) at 2 µg/ml
All lanes : Mouse brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 27 kDa
Immunofluorescence of EFHD2/SWS1 in Human brain tissue with ab106667 at 20 ug/mL.
ab106667, at 5 µg/ml, staining EFHD2/SWS1 in paraffin embedded Human brain tissue by immunohistochemistry.
ab106667 has been referenced in 1 publication.
- Fan CC et al. EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma. Sci Rep 7:14617 (2017). PubMed: 29097801