Overview

  • Product name

  • Description

    Rabbit polyclonal to EFHD2/SWS1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human EFHD2/SWS1 (N terminal) conjugated to keyhole limpet haemocyanin.

  • Positive control

    • Human Thymus and Tonsil tissues

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab119119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • Tissue specificity

    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • Sequence similarities

    Contains 2 EF-hand domains.
  • Cellular localization

    Membrane raft. In immature B-cell line WEHI231.
  • Information by UniProt
  • Database links

  • Alternative names

    • EF hand domain containing protein 2 antibody
    • EF hand domain family, member D2 antibody
    • EF-hand domain-containing protein D2 antibody
    • EFHD 2 antibody
    • EFHD2 antibody
    • EFHD2_HUMAN antibody
    • RP3-467K16.3 antibody
    • Swiprosin 1 antibody
    • Swiprosin-1 antibody
    • SWS1 antibody
    see all

Images

  • Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Human Thymus tissue using ab119119 at 5 µg/ml.
  • Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Human Tonsil tissue using ab119119 at 5 µg/ml.

References

This product has been referenced in:

  • Fan CC  et al. EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma. Sci Rep 7:14617 (2017). Read more (PubMed: 29097801) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab119119.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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