Anti-EFHD2/SWS1 antibody (ab240745)
Key features and details
- Rabbit polyclonal to EFHD2/SWS1
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-EFHD2/SWS1 antibody
See all EFHD2/SWS1 primary antibodies -
Description
Rabbit polyclonal to EFHD2/SWS1 -
Host species
Rabbit -
Tested applications
Suitable for: IPmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human EFHD2/SWS1 aa 1-50. The exact sequence is proprietary. (NP_077305.2).
Database link: Q96C19 -
Positive control
- IP: EFHD2/SWS1 IP in Jurkat whole cell lysate.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab240745 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IP | Use at 2-10 µg/mg of lysate. |
Target
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Function
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. -
Tissue specificity
Found in lymphocytes; preferentially expressed in CD8+ cells. -
Sequence similarities
Contains 2 EF-hand domains. -
Cellular localization
Membrane raft. In immature B-cell line WEHI231. - Information by UniProt
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Database links
- Entrez Gene: 79180 Human
- SwissProt: Q96C19 Human
- Unigene: 465374 Human
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Alternative names
- EF hand domain containing protein 2 antibody
- EF hand domain family, member D2 antibody
- EF-hand domain-containing protein D2 antibody
see all
Images
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Immunoprecipitation - Anti-EFHD2/SWS1 antibody (ab240745)
EFHD2/SWS1 was immunoprecipitated from Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab240745 at 6 µg/reaction. Western blot was performed from the immunoprecipitate using ab240745 at 0.4 µg/ml.
Lane 1: ab240745 IP in Jurkat whole cell lysate.
Lane 2: Control IgG IP in Jurkat whole cell lysate.Detection: Chemiluminescence with exposure time of 3 minutes.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab240745 has not yet been referenced specifically in any publications.
