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Signal Transduction Signaling Pathway Calcium Signaling Calcium Binding Proteins
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Anti-EFHD2/SWS1 antibody (ab240745)

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Immunoprecipitation - Anti-EFHD2/SWS1 antibody (ab240745)

    Key features and details

    • Rabbit polyclonal to EFHD2/SWS1
    • Suitable for: IP
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Protein
    Product image
    Recombinant Human EFHD2/SWS1 protein (ab132296)
    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-EFHD2/SWS1 antibody
      See all EFHD2/SWS1 primary antibodies
    • Description

      Rabbit polyclonal to EFHD2/SWS1
    • Host species

      Rabbit
    • Tested applications

      Suitable for: IPmore details
    • Species reactivity

      Reacts with: Human
    • Immunogen

      Synthetic peptide within Human EFHD2/SWS1 aa 1-50. The exact sequence is proprietary. (NP_077305.2).
      Database link: Q96C19

    • Positive control

      • IP: EFHD2/SWS1 IP in Jurkat whole cell lysate.
    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
    • Storage buffer

      pH: 7
      Preservative: 0.09% Sodium azide
      Constituent: Tris citrate/phosphate

      pH 7 to 8
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Signal Transduction
      • Signaling Pathway
      • Calcium Signaling
      • Calcium Binding Proteins

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Positive Controls

      • Jurkat whole cell lysate (ab30128)
      • Jurkat whole cell lysate (ab7899)
    • Recombinant Protein

      • Recombinant Human EFHD2/SWS1 protein (ab132296)
    • Related Products

      • Recombinant Human EFHD2/SWS1 protein (ab132296)

    Applications

    Our Abpromise guarantee covers the use of ab240745 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IP Use at 2-10 µg/mg of lysate.

    Target

    • Function

      May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
    • Tissue specificity

      Found in lymphocytes; preferentially expressed in CD8+ cells.
    • Sequence similarities

      Contains 2 EF-hand domains.
    • Cellular localization

      Membrane raft. In immature B-cell line WEHI231.
    • Target information above from: UniProt accession Q96C19 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 79180 Human
      • SwissProt: Q96C19 Human
      • Unigene: 465374 Human
      • Alternative names

        • EF hand domain containing protein 2 antibody
        • EF hand domain family, member D2 antibody
        • EF-hand domain-containing protein D2 antibody
        • EFHD 2 antibody
        • EFHD2 antibody
        • EFHD2_HUMAN antibody
        • RP3-467K16.3 antibody
        • Swiprosin 1 antibody
        • Swiprosin-1 antibody
        • SWS1 antibody
        see all

      Images

      • Immunoprecipitation - Anti-EFHD2/SWS1 antibody (ab240745)
        Immunoprecipitation - Anti-EFHD2/SWS1 antibody (ab240745)

        EFHD2/SWS1 was immunoprecipitated from Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab240745 at 6 µg/reaction. Western blot was performed from the immunoprecipitate using ab240745 at 0.4 µg/ml.

        Lane 1: ab240745 IP in Jurkat whole cell lysate.
        Lane 2: Control IgG IP in Jurkat whole cell lysate.

        Detection: Chemiluminescence with exposure time of 3 minutes.

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (0)

      Publishing research using ab240745? Please let us know so that we can cite the reference in this datasheet.

      ab240745 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

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