Anti-EGFR (phospho Y1068) antibody [EP774Y] (ab40815)

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ab40815 has been referenced in 44 publications.

  • Abou-Antoun TJ  et al. Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance. PLoS One 13:e0189711 (2018). PubMed: 29298329
  • Zhang Z  et al. Resolvin D1 promotes corneal epithelial wound healing and restoration of mechanical sensation in diabetic mice. Mol Vis 24:274-285 (2018). PubMed: 29643724
  • Zhang Y  et al. Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptor. Sci Rep 8:5994 (2018). PubMed: 29662125
  • Zhang C  et al. Blocking of the EGFR-STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma. Exp Ther Med 15:4995-5000 (2018). PubMed: 29805522
  • Steger CM  et al. Gene therapy with antisense oligonucleotides silencing c-myc reduces neointima formation and vessel wall thickness in a mouse model of vein graft disease. Exp Mol Pathol 105:1-9 (2018). IHC-P ; Mouse . PubMed: 29775572
  • Herring CA  et al. Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut. Cell Syst 6:37-51.e9 (2018). PubMed: 29153838
  • Hsu PY  et al. Cordycepin and a preparation fromCordyceps militarisinhibit malignant transformation and proliferation by decreasing EGFR and IL-17RA signaling in a murine oral cancer model. Oncotarget 8:93712-93728 (2017). PubMed: 29212184
  • Yang HK  et al. Downregulation of LRIG2 expression inhibits angiogenesis of glioma via EGFR/VEGF-A pathway. Oncol Lett 14:4021-4028 (2017). PubMed: 28943909
  • Roselló-Díez A  et al. Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth. Elife 6:N/A (2017). PubMed: 28741471
  • Dombernowsky SL  et al. Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect theApcMinmodel of colorectal cancer. Oncotarget 8:108303-108315 (2017). PubMed: 29312533
  • Chen J  et al. A role for ErbB signaling in the induction of reactive astrogliosis. Cell Discov 3:17044 (2017). PubMed: 29238610
  • Horita H  et al. Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton. Neoplasia 19:346-353 (2017). WB ; Human . PubMed: 28319808
  • Wodziak D  et al. Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration. PLoS One 11:e0164968 (2016). Rat . PubMed: 27764193
  • Currier MG  et al. EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression. PLoS Pathog 12:e1005622 (2016). IF . PubMed: 27152417
  • Atiq R  et al. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget 7:18694-704 (2016). PubMed: 26959890
  • Derangère V  et al. Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer? Oncotarget 7:9309-21 (2016). WB . PubMed: 26824184
  • Wolf C  et al. ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phosholipase C ?1 and protein kinase C pathways. Sci Rep 6:39780 (2016). PubMed: 28004780
  • Kang MH  et al. Antitumor Activity of HM781-36B, alone or in Combination with Chemotherapeutic Agents, in Colorectal Cancer Cells. Cancer Res Treat 48:355-64 (2016). WB . PubMed: 25761479
  • Fu Y  et al. Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype. Sci Rep 5:13347 (2015). PubMed: 26289340
  • Zhu Z  et al. Phosphorylated AKT1 is associated with poor prognosis in esophageal squamous cell carcinoma. J Exp Clin Cancer Res 34:95 (2015). IHC-P ; Human . PubMed: 26338103
  • Darr J  et al. Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells. Mol Cancer 14:167 (2015). WB ; Mouse . PubMed: 26370283
  • Minder P  et al. EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation. Neoplasia 17:634-49 (2015). PubMed: 26408256
  • Dombernowsky SL  et al. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17. Nat Commun 6:7518 (2015). PubMed: 26108729
  • Furcht CM  et al. EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR. Sci Signal 8:ra46 (2015). PubMed: 25969544
  • Dong A  et al. Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem 290:8016-27 (2015). PubMed: 25666625
  • Hutchinson KE  et al. ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma. Oncotarget 6:22348-60 (2015). PubMed: 26084293
  • Lu YY  et al. 1118-20, an indazole diarylurea compound, inhibits hepatocellular carcinoma HepG2 proliferation and tumour angiogenesis involving Wnt/ß-catenin pathway and receptor tyrosine kinases. J Pharm Pharmacol 67:1393-405 (2015). WB ; Human . PubMed: 26076716
  • Andersson N  et al. Sensitivity of human granulosa cell tumor cells to epidermal growth factor receptor inhibition. J Mol Endocrinol 52:223-34 (2014). PubMed: 24463098
  • Nakamura T  et al. LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis. J Clin Invest 124:385-97 (2014). IHC . PubMed: 24316976
  • Furcht CM  et al. Multivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cells. J Cell Sci 127:3555-67 (2014). PubMed: 24951116
  • Martel G  et al. The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs). PLoS One 8:e59116 (2013). WB ; Human . PubMed: 23527104
  • Kiritsi D  et al. Novel and recurrent AAGAB mutations: clinical variability and molecular consequences. J Invest Dermatol 133:2483-6 (2013). WB ; Human . PubMed: 23563198
  • Lee HJ  et al. Noncovalent wild-type-sparing inhibitors of EGFR T790M. Cancer Discov 3:168-81 (2013). PubMed: 23229345
  • Simons AL  et al. The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation. Lab Invest 93:711-9 (2013). PubMed: 23608756
  • Yuan Y  et al. Acetyl-11-keto-beta-boswellic acid (AKBA) prevents human colonic adenocarcinoma growth through modulation of multiple signaling pathways. Biochim Biophys Acta 1830:4907-16 (2013). PubMed: 23850473
  • Hattoum A  et al. Expression of hepatocyte epidermal growth factor receptor, FAS and glypican 3 in EpCAM-positive regenerative clusters of hepatocytes, cholangiocytes, and progenitor cells in human liver failure. Hum Pathol 44:743-9 (2013). PubMed: 23114924
  • Able RA  et al. Low Concentration Microenvironments Enhance the Migration of Neonatal Cells of Glial Lineage. Cell Mol Bioeng 5:N/A (2012). PubMed: 24285985
  • Wong VW  et al. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol 14:401-8 (2012). PubMed: 22388892
  • Langhammer S  et al. Inhibition of poxvirus spreading by the anti-tumor drug Gefitinib (Iressa). Antiviral Res 89:64-70 (2011). WB ; Human . PubMed: 21094187
  • Huang Z  et al. MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma. Cancer Res 71:2582-9 (2011). PubMed: 21427358
  • Wang H  et al. Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity. Neoplasia 13:461-71 (2011). PubMed: 21532887
  • Hölsken A  et al. EGFR Signaling Regulates Tumor Cell Migration in Craniopharyngiomas. Clin Cancer Res 17:4367-77 (2011). IHC-P ; Human . PubMed: 21562037
  • Naumov GN  et al. Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clin Cancer Res 15:3484-94 (2009). IHC-P ; Human . PubMed: 19447865
  • Zheng H  et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455:1129-33 (2008). IHC-FoFr ; Mouse . PubMed: 18948956


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