Overview

  • Product name

  • Description

    Rabbit polyclonal to EI24
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 23-72 (ICTISKLDAR IQQKREEQRR RRASSVLAQR RAQSIERKQE SEPRIVSRIF) of Human EI24 (NP_001007278).

  • Positive control

    • HeLa cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab130957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 30 kDa.

Target

  • Function

    Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy.
  • Involvement in disease

    Note=EI24 is on a chromosomal region frequently deleted in solid tumors, and it is thought to play a role in breast and cervical cancer. Particularly, expression analysis of EI24 in cancerous tissues shows that EI24 loss is associated with tumor invasiveness.
  • Sequence similarities

    Belongs to the EI24 family.
  • Cellular localization

    Nucleus membrane. Cytoplasm. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Ectopic P granules autophagy protein 4 homolog antibody
    • Ei24 antibody
    • EI24_HUMAN antibody
    • EPG4 antibody
    • Etoposide induced 2.4 mRNA antibody
    • Etoposide-induced protein 2.4 homolog antibody
    • p53-induced gene 8 protein antibody
    • PIG8 antibody
    • TP53I8 antibody
    • Tumor protein p53 inducible protein 8 antibody
    see all

Images

  • Anti-EI24 antibody (ab130957) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size: 30 kDa



    12% SDS PAGE

References

ab130957 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab130957.
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