Overview

  • Product name
    Anti-EID2 antibody - C-terminal
  • Description
    Rabbit Polyclonal to EID2 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human EID2 aa 182-216 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8N6I1

  • Positive control
    • Mouse spleen tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab174887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 25 kDa.

Target

  • Function
    Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
  • Tissue specificity
    Most abundantly expressed in placenta. Highly expressed in liver, brain, heart, skeletal muscle, and kidney.
  • Domain
    The N-terminal portion of EID2 is required for nuclear localization.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CREBBP/EP300 inhibitor 2 antibody
    • CREBBP/EP300 inhibitory protein 2 antibody
    • CRI2 antibody
    • E1A like inhibitor of differentiation 2 antibody
    • EID-1-like inhibitor of differentiation 2 antibody
    • EID-2 antibody
    • EID2 antibody
    • EID2_HUMAN antibody
    • EP300-interacting inhibitor of differentiation 2 antibody
    see all

Images

  • Anti-EID2 antibody - C-terminal (ab174887) at 1/100 dilution + Mouse spleen tissue lysates at 15 µg

    Predicted band size: 25 kDa

References

ab174887 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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