Overview

  • Product name

  • Description

    Rabbit polyclonal to eIF3l
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Cow, Human, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to Human eIF3l aa 330-564.
    Database link: Q9Y262

  • Positive control

    • Mouse brown adipose and white adipose whole cell lysates.
  • General notes

     This product was previously labelled as IF3EI

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: PBS, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154527 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.

Target

  • Function

    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • Sequence similarities

    Belongs to the eIF-3 subunit L family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

    see all
  • Alternative names

    • eIEF associated protein HSPC021 antibody
    • EIF3EIP antibody
    • eif3l antibody
    • EIF3L_HUMAN antibody
    • EIF3S11 antibody
    • EIF3S6IP antibody
    • Eukaryotic translation initiation factor 3 subunit 6 interacting antibody
    • Eukaryotic translation initiation factor 3 subunit 6-interacting protein antibody
    • Eukaryotic translation initiation factor 3 subunit E-interacting protein antibody
    • Eukaryotic translation initiation factor 3 subunit L antibody
    • eukaryotic translation initiation factor 3, subunit E interacting antibody
    • HSPC021 antibody
    • HSPC025 antibody
    • MSTP005 antibody
    see all

Images

  • All lanes : Anti-eIF3l antibody (ab154527) at 1/1000 dilution

    Lane 1 : Mouse brown adipose whole cell lysate
    Lane 2 : Mouse white adipose whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Predicted band size: 66 kDa



    7.5% SDS PAGE

References

ab154527 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154527.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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