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ab2606 has been referenced in 20 publications.

  • Tian Y  et al. Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway. J Cell Physiol 235:442-453 (2020). PubMed: 31332784
  • Wang M  et al. Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression. Onco Targets Ther 12:4643-4654 (2019). PubMed: 31354297
  • Wang Q  et al. The mTOR Signal Pathway Is Overactivated in Human Lymphatic Malformations. Lymphat Res Biol N/A:N/A (2019). PubMed: 31381473
  • Guo GF  et al. Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data. World J Gastroenterol 25:1840-1853 (2019). PubMed: 31057298
  • Lai WS & Ding YL GNG7 silencing promotes the proliferation and differentiation of placental cytotrophoblasts in preeclampsia rats through activation of the mTOR signaling pathway. Int J Mol Med 43:1939-1950 (2019). PubMed: 30864685
  • Ilic BB  et al. VHL Dependent Expression of REDD1 and PDK3 Proteins in Clear-cell Renal Cell Carcinoma. J Med Biochem 37:31-38 (2018). PubMed: 30581339
  • Jiang Y  et al. TIPE2 governs macrophage polarization via negative regulation of mTORC1. Mol Med Rep 17:952-960 (2018). PubMed: 29115630
  • Chen DP  et al. 1,25-Dihydroxyvitamin D3 inhibits the proliferation of rat mesangial cells induced by high glucose via DDIT4. Oncotarget 9:418-427 (2018). PubMed: 29416624
  • Li H  et al. MEN1/Menin regulates milk protein synthesis through mTOR signaling in mammary epithelial cells. Sci Rep 7:5479 (2017). PubMed: 28710500
  • Freis P  et al. mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines. Oncotarget 8:20974-20987 (2017). WB ; Mouse . PubMed: 28423496
  • Taneike M  et al. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. PLoS One 11:e0152628 (2016). PubMed: 27023784
  • Shen X  et al. EMC6/TMEM93 suppresses glioblastoma proliferation by modulating autophagy. Cell Death Dis 7:e2043 (2016). PubMed: 26775697
  • Jiang Z  et al. Blocking mammalian target of rapamycin alleviates bone cancer pain and morphine tolerance via µ-opioid receptor. Int J Cancer 138:2013-20 (2016). WB ; Rat . PubMed: 26566757
  • Banduseela VC  et al. Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle. Physiol Genomics 45:477-86 (2013). PubMed: 23572537
  • Raben N  et al. Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder--murine Pompe disease. Autophagy 6:1078-89 (2010). WB . PubMed: 20861693
  • Jacobson BA  et al. Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma. Br J Cancer 101:424-31 (2009). WB ; Human . PubMed: 19603014
  • Zhang L  et al. Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells. J Biol Chem 282:5790-800 (2007). PubMed: 17170115
  • Patel MR  et al. Ras pathway activation in malignant mesothelioma. J Thorac Oncol 2:789-95 (2007). WB ; Human . PubMed: 17805054
  • Larsson O  et al. Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors. Cancer Res 67:6814-24 (2007). PubMed: 17638893
  • Culjkovic B  et al. eIF4E is a central node of an RNA regulon that governs cellular proliferation. J Cell Biol 175:415-26 (2006). PubMed: 17074885

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