Key features and details
- Rabbit polyclonal to ELAC2 - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ELAC2 antibody - C-terminal
See all ELAC2 primary antibodies
DescriptionRabbit polyclonal to ELAC2 - C-terminal
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Rat
Fusion protein corresponding to Human ELAC2 (C terminal). (Residues near the C terminus.) The identity of the protein fusion partner is GST. Gene Accssion: BC001939
Database link: Q9BQ52
- Hela and Lovo cell lysates; Human gastric cancer tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197944 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
|WB||1/200 - 1/1000. Predicted molecular weight: 92 kDa.|
FunctionZinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Tissue specificityWidely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
Involvement in diseaseDefects in ELAC2 may be a cause of susceptibility to prostate cancer (PC) [MIM:176807]. It is a malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
Sequence similaritiesBelongs to the RNase Z family.
- Information by UniProt
- COXPD17 antibody
- elaC homolog 2 (E. coli) antibody
- ElaC homolog protein 2 antibody
All lanes : Anti-ELAC2 antibody - C-terminal (ab197944) at 1/250 dilution
Lane 1 : Lovo cell lysate
Lane 2 : Hela cell lysate
Lysates/proteins at 40 µg per lane.
Predicted band size: 92 kDa
Exposure time: 1 minute
6% SDS PAGE
Immunohistochemical analysis of formalin fixed paraffin embedded Human gastric cancer tissue labeling ELAC2 with ab197944 at a 1/30 dilution.
ab197944 has not yet been referenced specifically in any publications.