Anti-Elafin/ESI antibody (ab192345)

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Overview

  • Product name

    Anti-Elafin/ESI antibody
    See all Elafin/ESI primary antibodies

  • Description

    Rabbit polyclonal to Elafin/ESI

  • Host species

    Rabbit

  • Specificity

    ab192345 detects endogenous levels of Elafin/ESI protein.

  • Tested applications

    Suitable for: IHC-P, WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant full length protein corresponding to Human Elafin/ESI aa 1-117.
    Sequence:

    MRASSFLIVV VFLIAGTLVL EAAVTGVPVK GQDTVKGRVP FNGQDPVKGQ VSVKGQDKVK AQEPVKGPVS TKPGSCPIIL IRCAMLNPPN RCLKDTDCPG IKKCCEGSCG MACFVPQ


    Database link: P19957

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • General notes

    Previously labelled as Elafin/Skalp. 

Properties

Applications

Our Abpromise guarantee covers the use of ab192345 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 12 kDa.

Target

  • Function

    Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis.

  • Sequence similarities

    Contains 1 WAP domain.

  • Domain

    Consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • Cementoin antibody
      • ELAF_HUMAN antibody
      • Elafin antibody
      • Elafin/Skalp antibody
      • Elastase Specific Inhibitor antibody
      • Elastase-specific inhibitor antibody
      • ES 1 antibody
      • ESI antibody
      • Peptidase inhibitor 3 antibody
      • Peptidase inhibitor 3, skin derived antibody
      • PI 3 antibody
      • PI-3 antibody
      • PI3 antibody
      • Pre elafin antibody
      • Protease inhibitor 3 skin derived antibody
      • Protease inhibitor 3, skin derived (SKALP) antibody
      • Protease inhibitor WAP3 antibody
      • SKALP antibody
      • Skin derived Anti leukoproteinase antibody
      • Skin-derived antileukoproteinase antibody
      • Trappin 2 antibody
      • WAP four disulfide core domain 14 antibody
      • WAP four disulfide core domain protein 14 antibody
      • WAP four-disulfide core domain protein 14 antibody
      • WAP3 antibody
      • WFDC14 antibody
      see all

    References

    ab192345 has not yet been referenced specifically in any publications.

    Publishing research using ab192345? Please let us know so that we can cite the reference in this datasheet.

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