Overview

  • Product name

    Ellagic acid, casein kinase 2 (CK2) inhibitor
  • Description

    Selective, casein kinase 2 (CK2) inhibitor
  • Biological description

    Selective, ATP-competitive casein kinase 2 (CK2) inhibitor (Ki = 20 nM). Exhibits a multitude of biological activities including antioxidant, antiproliferative and pro-apoptotic activity.
  • Purity

    > 99%
  • CAS Number

    476-66-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • Molecular weight

    302.20
  • Molecular formula

    C14H6O8
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO to 1 mM and in ethanol to 1 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Tree bark

  • Research areas

References

This product has been referenced in:

  • Cozza G  et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006). Read more (PubMed: 16610779) »
  • Seeram NP  et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-7 (2005). Read more (PubMed: 15936648) »
  • Han DH  et al. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res 26:3601-6 (0). Read more (PubMed: 17094489) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120622.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up