Overview

  • Product name
    Anti-ELOVL2 antibody [EPR11880]
  • Description
    Rabbit monoclonal [EPR11880] to ELOVL2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IP, WBmore details
    Unsuitable for: ICC or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ELOVL2 aa 250 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9NXB9

  • Positive control
    • Rat liver, Mouse testis, Fetal liver and Mouse liver lysates
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab176327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/10 - 1/100.
WB 1/1000 - 1/10000. Predicted molecular weight: 34 kDa.
  • Application notes
    Is unsuitable for ICC or IHC-P.

    • Target

    • Function
      Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.
    • Tissue specificity
      Liver and testis.
    • Sequence similarities
      Belongs to the ELO family.
    • Domain
      The di-lysine motif may confer endoplasmic reticulum localization.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
      • Alternative names
        • 3 keto acyl CoA synthase ELOVL2 antibody
        • 3-keto acyl-CoA synthase Elovl2 antibody
        • Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2 antibody
        • Elongation of very long chain fatty acids protein 2 antibody
        • ELOV2_HUMAN antibody
        • ELOVL fatty acid elongase 2 antibody
        • Elovl2 antibody
        • FLJ20334 antibody
        • OTTHUMP00000016029 antibody
        • SSC2 antibody
        see all

      Images

      • Immunoprecipitation - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        Immunoprecipitation - Anti-ELOVL2 antibody [EPR11880] (ab176327)

        Western blot analysis on immunoprecipitation pellet from mouse liver lysate labeling ELOVL2 using ab176327 at a 1/10 dilution.

      • Western blot - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        Western blot - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        All lanes : Anti-ELOVL2 antibody [EPR11880] (ab176327) at 1/1000 dilution

        Lane 1 : Rat liver lysate
        Lane 2 : Mouse testis lysate
        Lane 3 : Fetal liver lysate
        Lane 4 : Mouse liver lysate

        Lysates/proteins at 10 µg per lane.

        Predicted band size: 34 kDa

      References

      This product has been referenced in:
      • Song L  et al. Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. Sci Rep 7:41604 (2017). WB ; Rat . Read more (PubMed: 28169366) »
      • Yan M  et al. Identification of SPOP related metabolic pathways in prostate cancer. Oncotarget 8:103032-103046 (2017). WB . Read more (PubMed: 29262542) »

      See all 2 Publications for this product

      Publishing research using ab176327? Please let us know so that we can cite the reference in this datasheet.

      Customer reviews and Q&As

      Submit a review Submit a question

      There are currently no Customer reviews or Questions for ab176327.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

      Sign up