Recombinant
RabMAb

Recombinant Anti-ELOVL2 antibody [EPR11880] (ab176327)

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Overview

  • Product name

    Anti-ELOVL2 antibody [EPR11880]
    See all ELOVL2 primary antibodies

  • Description

    Rabbit monoclonal [EPR11880] to ELOVL2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IP, WBmore details
    Unsuitable for: ICC or IHC-P

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ELOVL2 aa 250 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9NXB9

  • Positive control

    • Rat liver, Mouse testis, Fetal liver and Mouse liver lysates

  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab176327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/10 - 1/100.
WB 1/1000 - 1/10000. Predicted molecular weight: 34 kDa.
  • Application notes
    Is unsuitable for ICC or IHC-P.

    • Target

    • Function

      Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.

    • Tissue specificity

      Liver and testis.

    • Sequence similarities

      Belongs to the ELO family.

    • Domain

      The di-lysine motif may confer endoplasmic reticulum localization.

    • Cellular localization

      Endoplasmic reticulum membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • 3 keto acyl CoA synthase ELOVL2 antibody
        • 3-keto acyl-CoA synthase Elovl2 antibody
        • Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2 antibody
        • Elongation of very long chain fatty acids protein 2 antibody
        • ELOV2_HUMAN antibody
        • ELOVL fatty acid elongase 2 antibody
        • Elovl2 antibody
        • FLJ20334 antibody
        • OTTHUMP00000016029 antibody
        • SSC2 antibody
        see all

      Images

      • Immunoprecipitation - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        Immunoprecipitation - Anti-ELOVL2 antibody [EPR11880] (ab176327)

        Western blot analysis on immunoprecipitation pellet from mouse liver lysate labeling ELOVL2 using ab176327 at a 1/10 dilution.

      • Western blot - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        Western blot - Anti-ELOVL2 antibody [EPR11880] (ab176327)
        All lanes : Anti-ELOVL2 antibody [EPR11880] (ab176327) at 1/1000 dilution

        Lane 1 : Rat liver lysate
        Lane 2 : Mouse testis lysate
        Lane 3 : Fetal liver lysate
        Lane 4 : Mouse liver lysate

        Lysates/proteins at 10 µg per lane.

        Predicted band size: 34 kDa

      References

      This product has been referenced in:

      • Sarr O  et al. Dietary EPA and DHA prevent changes in white adipose tissue omega-3 PUFA and oxylipin content associated with a Fads2 deficiency. J Nutr Biochem 63:140-149 (2019). Read more (PubMed: 30368227) »
      • Song L  et al. Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. Sci Rep 7:41604 (2017). WB ; Rat . Read more (PubMed: 28169366) »
      See all 3 Publications for this product

      Publishing research using ab176327? Please let us know so that we can cite the reference in this datasheet.

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