Overview

  • Product name
  • Description
    Rabbit polyclonal to ELP2
  • Host species
    Rabbit
  • Specificity
    Specific for StIP-1 at 92kDa, which may appear as a doublet. Also recognizes a second band at ~70kDa.
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Mouse ELP2 aa 679-693 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Sequence:

    CSPDSKYFFTGSRDKK

  • Positive control
    • BAF-3 RIPA cell lysate
  • General notes

    Previously labelled as STATIP1.

Properties

Applications

Our Abpromise guarantee covers the use of ab18048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
WB
  • Application notes
    IP: Use at 1 - 4µg/0.5mg of lysate.
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 63 kDa).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Regulates the ligand-dependent activation of STAT3.
      Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
    • Sequence similarities
      Belongs to the WD repeat ELP2 family.
      Contains 14 WD repeats.
    • Cellular localization
      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AU023723 antibody
      • Elongation protein 2 homolog (S. cerevisiae) antibody
      • Elongator acetyltransferase complex subunit 2 antibody
      • Elongator complex protein 2 antibody
      • elongator protein 2 antibody
      • ELP2 antibody
      • ELP2_HUMAN antibody
      • Epl2 antibody
      • FLJ10879 antibody
      • SHINC 2 antibody
      • SHINC-2 antibody
      • SHINC2 antibody
      • signal transducer and activator of transcription 3 interacting protein 1 antibody
      • signal transducer and activator of transcription interacting protein 1 antibody
      • STAT3 interacting protein 1 antibody
      • Stat3 interacting protein antibody
      • STAT3-interacting protein 1 antibody
      • STATIP 1 antibody
      • STATIP1 antibody
      • STATIP1 protein antibody
      • StIP antibody
      • StIP1 antibody
      see all

    References

    ab18048 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    1-3 of 3 Abreviews or Q&A

    Question
    Answer

    Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

    I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement with the order number xxx with ab110362. The estimated delivery date is February 21. I hope that is OK.

    To check the status of the order please contact our Customer Service team and reference this number.

    Please note that this free of charge replacement vial is also covered by our Abpromise guarantee. Should you still be experiencing difficulties, or if you have any further questions, please do not hesitate to let us know.

    I wish you the best of luck with your research.

    Read More

    Answer

    Thank you for contacting us.
    I am sorry to hear that this antibody is not giving the expected results.

    I'd like to offer you a free of charge replacement with either another lot of ab18048, or ab110362 (tested in WB, human) or ab56185 (tested in WB, but not yet with endogenous protein). Alternatively, a replacement with an antibody for a different target protein can be arranged. Other optionswould be a credit or a refund.

    Please let me know which option you would prefer.

    I look forward to hear back from you.

    Read More
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Cell lysate - whole cell (Lung)
    Gel Running Conditions
    Reduced Denaturing (8%)
    Loading amount
    20 µg
    Specification
    Lung
    Blocking step
    Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10%

    Abcam user community

    Verified customer

    Submitted Jul 01 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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