Emodin, 11beta-HSD1 inhibitor (ab141454)
Key features and details
- Potent 11β-HSD1 inhibitor. Antioxidant agent.
- CAS Number: 518-82-1
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Emodin, 11beta-HSD1 inhibitor -
Description
Potent 11β-HSD1 inhibitor. Antioxidant agent. -
Biological description
Potent, selective 11β-HSD1 inhibitor (IC50 values are 186 and 86 nM for human and mouse 11beta-HSD1 respectively). Antioxidant agent. Activates caspase-3, -8 and -9. Increases Bax and decreases Bcl-2. Antidyslipidemic in vivo. Orally active.
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Purity
> 98% -
CAS Number
518-82-1 -
Chemical structure
Properties
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Chemical name
1,3,8-Trihydroxy-6-methylanthracene-9,10-dione -
Molecular weight
270.24 -
Molecular formula
C15H10O5 -
PubChem identifier
3220 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O -
Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab141454 has not yet been referenced specifically in any publications.