Overview

  • Product name
    Anti-emopamil binding protein antibody - C-terminal
    See all emopamil binding protein primary antibodies
  • Description
    Rabbit polyclonal to emopamil binding protein - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 201-230 of Human emopamil binding protein (NP_006570.1)

  • Positive control
    • MCF7 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab156443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 26 kDa.

Target

  • Function
    Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
  • Pathway
    Steroid biosynthesis; cholesterol biosynthesis.
  • Involvement in disease
    Defects in EBP are the cause of chondrodysplasia punctata X-linked dominant type 2 (CDPX2) [MIM:302960]; also known as Conradi-Hunermann-Happle syndrome. CDP is a clinically and genetically heterogeneous disorder characterized by punctiform calcification of the bones. The key clinical features of CDPX2 are chondrodysplasia punctata, linear ichthyosis, cataracts and short stature. CDPX2 is a rare disorder of defective cholesterol biosynthesis, biochemically characterized by an increased amount of 8-dehydrocholesterol and cholest-8(9)-en-3-beta-ol in the plasma and tissues.
  • Sequence similarities
    Belongs to the EBP family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase antibody
    • CDPX2 antibody
    • CHO2 antibody
    • Cholestenol Delta-isomerase antibody
    • CPX antibody
    • CPXD antibody
    • D8-D7 sterol isomerase antibody
    • Delta(8)-Delta(7) sterol isomerase antibody
    • ebp antibody
    • EBP_HUMAN antibody
    • Emopamil-binding protein antibody
    • Msi antibody
    see all

Images

  • Anti-emopamil binding protein antibody - C-terminal (ab156443) at 1/100 dilution + MCF7 cell lysate at 35 µg

    Predicted band size: 26 kDa

References

ab156443 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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