Key features and details
- Rabbit polyclonal to EMR2
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-EMR2 antibody
See all EMR2 primary antibodies
DescriptionRabbit polyclonal to EMR2
Specificityab75190 detects endogenous levels of total EMR2 protein.
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
Synthetic peptide derived from an internal region of human EMR2
- HeLa cell extract
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab75190 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Our Abpromise guarantee covers the use of ab75190 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 91 kDa.|
FunctionReceptor probably involved in cell attachment.
Tissue specificityExpression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 5 EGF-like domains.
Contains 1 GPS domain.
DomainThe GPS domain is necessary, but not sufficient for receptor cleavage, which require the entire extracellular stalk.
Binding to chondroitin sulfate is mediated by the fourth EGF domain.
modificationsAutoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
Cellular localizationCell membrane.
- Information by UniProt
- CD 312 antibody
- CD 312 antigen antibody
- CD312 antibody
ab75190 has not yet been referenced specifically in any publications.