Anti-EMX2 antibody (ab171818)

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.2
Constituent: 100% PBS
Concentration information loading...
Purity

Protein A purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab171818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Predicted molecular weight: 28 kDa.

Function

Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
Tissue specificity

Cerebral cortex.
Involvement in disease

Defects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
Sequence similarities

Belongs to the EMX homeobox family.
Contains 1 homeobox DNA-binding domain.
Cellular localization

Nucleus.
Target information above from: UniProt accession Q04743 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 2018 Human
- Omim: 600035 Human
- SwissProt: Q04743 Human
- Unigene: 202095 Human
Alternative names
- Empty spiracles homeobox 2 antibody
- Empty spiracles homolog 2 (Drosophila) antibody
- Empty spiracles homolog 2 antibody
- Empty spiracles like protein 2 antibody
- Empty spiracles-like protein 2 antibody
- EMX 2 antibody
- EMX2 antibody
- EMX2_HUMAN antibody
- Homeobox protein EMX 2 antibody
- Homeobox protein EMX2 antibody
see all

ab171818 has not yet been referenced specifically in any publications.

Publishing research using ab171818? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As