Product nameAnti-EMX2 antibody
See all EMX2 primary antibodies
DescriptionRabbit polyclonal to EMX2
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Chicken, Cow, Dog, Human, Pig, Zebrafish
Synthetic peptide corresponding to Mouse EMX2 aa 100-200 conjugated to keyhole limpet haemocyanin.
(Peptide available as
- This antibody gave a positive signal in both Mouse brain and hippocampus tissue lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS. pH 7.4
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab94713 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).|
|ICC/IF||Use at an assay dependent concentration.|
FunctionTranscription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
Tissue specificityCerebral cortex.
Involvement in diseaseDefects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
Sequence similaritiesBelongs to the EMX homeobox family.
Contains 1 homeobox DNA-binding domain.
- Information by UniProt
- Empty spiracles homeobox 2 antibody
- Empty spiracles homolog 2 (Drosophila) antibody
- Empty spiracles homolog 2 antibody
All lanes : Anti-EMX2 antibody (ab94713) at 1 µg/ml
Lane 1 : Mouse Hippocampus Tissue Lysate
Lane 2 : Brain (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 28 kDa
Additional bands at: 260 kDa (possible non-specific binding), 76 kDa (possible non-specific binding)
Exposure time: 16 minutes
ab94713 has not yet been referenced specifically in any publications.