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Apolipoprotein B

Function

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

Post-translational modifications

Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.

Cellular localization

  • Cytoplasm
  • Secreted
  • Lipid droplet

Alternative names

  • Apolipoprotein B-100
  • Apo B-100
  • Apob

Target type

Proteins

Molecular weight

509432Da