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AB197434

Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative

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ab197434 can be used for quantitative measurement of 17 Human Adhesion Molecule.

View Alternative Names

CD166, MEMD, ALCAM, CD166 antigen, Activated leukocyte cell adhesion molecule, CD56, NCAM, NCAM1, Neural cell adhesion molecule 1, N-CAM-1, NCAM-1, CD326, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1, EPCAM, Epithelial cell adhesion molecule, Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, EGP, EGP314, hEGP314, CDHP, CDH3, Cadherin-3, Placental cadherin, P-cadherin, CD62E, ELAM1, SELE, E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, ELAM-1, LECAM2, CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1, CD66a, BGP, BGP1, CEACAM1, Cell adhesion molecule CEACAM1, Biliary glycoprotein 1, Carcinoembryonic antigen-related cell adhesion molecule 1, BGP-1, CEA cell adhesion molecule 1, CD62L, LNHR, LYAM1, SELL, L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, TQ1, gp90-MEL, LAM-1, LECAM1, CD239, LU, MSK19, BCAM, Basal cell adhesion molecule, Auberger B antigen, B-CAM cell surface glycoprotein, F8/G253 antigen, Lutheran antigen, Lutheran blood group glycoprotein, CD50, Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, ICAM3, CD62P, GMRP, GRMP, SELP, P-selectin, CD62 antigen-like family member P, Granule membrane protein 140, Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, GMP-140, LECAM3, PADGEM, CD54, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, ICAM1, CD102, Intercellular adhesion molecule 2, ICAM-2, ICAM2, CD324, CDHE, UVO, CDH1, Cadherin-1, CAM 120/80, Epithelial cadherin, Uvomorulin, E-cadherin, CD144, Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CDH5, CD106, Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, VCAM1, KIAA0343, NRCAM, Neuronal cell adhesion molecule, Nr-CAM, Neuronal surface protein Bravo, NgCAM-related cell adhesion molecule, hBravo, Ng-CAM-related

3 Images
Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)

Standard Curve obtained using Abcam Human Adhesion Molecule Antibody Array (10 Targets) - Quantitative (ab197434).

Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)

Array map for Abcam Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (ab197434).

Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (AB197434)

Assay summary for Abcam Human Adhesion Molecule Antibody Array (17 Targets) - Quantitative (ab197434).

Key facts

Reacts with

Human

Target

ALCAM

target

Detection method

Fluorescent

Assay Platform

Multiplex

Sample types

Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate

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Product details

ab197434 can be used for quantitative measurement of 17 Human Adhesion Molecule. Suitable for serum, plasma, cell culture media, other body fluids, cell and tissue lysates.

Target names: ALCAM, BCAM, CEACAM-1, E-Cadherin, EpCAM,E-Selectin, ICAM-1, ICAM-2, ICAM-3, L-Selectin, NCAM-1, NrCAM, P-Cadherin, P-Selectin, PECAM-1, VCAM-1, VE-Cadherin.

The analytes measured by this kit are split across a single array on the same slide, provided in the kit.

Quantitative antibody arrays can be used to quantitate up to 40 cytokines with as little as 50 µL of sample. Arrays are available for 400 human and 200 mouse proteins. Each glass slide is spotted with 16 identical antibody arrays and is provided with a 16 well gasket to allow separate samples to be applied to each array.Each antibody is spotted in quadruplicate on each array. For reproducible quantitation, eight of the arrays are used with a cocktail of protein standards to produce a standard curve. The same 8 standard curve arrays can be used across multiple slides, allowing measurement of 22 experimental samples with 2 slides, 36 with 3 slides etc. For high through-put, 4 slides can be nested into a tray matching a standard microplate (not supplied), allowing automated processing with a liquid handling workstation. Array processing can be completed within one working day and arrays can be analyzed with a wide number of laser glass slide array / gene microarray scanners (see scanner requirements at ). If you don’t have a suitable scanner then we recommend our membrane antibody arrays, which can be analyzed with any WB chemiluminescent reader. See below for a schematic protocol, the fluorophore is a dye with equivalent to excitation/emission to Cy3.

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What's included?

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Product protocols

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Target data

Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed : 15048703, PubMed : 15496415, PubMed : 16352806, PubMed : 23169771, PubMed : 24945728, PubMed : 7760007). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed : 15048703, PubMed : 16352806, PubMed : 24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed : 15294938, PubMed : 16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed : 15496415, PubMed : 16352806). Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation (PubMed : 29263213). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed : 24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed : 23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed : 15496415, PubMed : 23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).. Isoform 3. Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.
See full target information ALCAM

Additional targets

BCAM,CDH1,CDH3,CDH5,CEACAM1,EPCAM,ICAM1,ICAM2,ICAM3,NCAM1,NRCAM,PECAM1,SELE,SELL,SELP,VCAM1
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Product promise

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