ab193656 can be used for the simultaneous detection of 120 Human Cytokine proteins in serum, plasma, cell culture media and other liquid samples types.
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- International orthopaedics 47:2409-24172023Meniscus repair via collagen matrix wrapping and bone marrow injection: clinical and biomolecular study.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPaweł Bąkowski,Adam Aron Mieloch,Filip Porzucek,Monika Mańkowska,Kinga Ciemieniewska-Gorzela,Jakub Naczk,Tomasz Piontek,Jakub Dalibor RybkaPubMed 36764942
- Cell transplantation 31:96368972211044522022Endometrial Cancer-Infiltrating Mesenchymal Stem Cells Exhibit Immunosuppressive Effects.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKai-Hung Wang,Yu-Hsun Chang,Tomor Harnod,Dah-Ching DingPubMed 35712817
- Aging 14:297-3152022TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuolin Zhang,Xin Luo,Zian Wang,Jianbin Xu,Wei Zhang,Engeng Chen,Qing Meng,Di Wang,Xuefeng Huang,Wei Zhou,Zhangfa SongPubMed 35022331
- The Journal of allergy and clinical immunology 149:275-2912021P17 induces chemotaxis and differentiation of monocytes via MRGPRX2-mediated mast cell-line activation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKarthi Duraisamy,Kailash Singh,Mukesh Kumar,Benjamin Lefranc,Elsa Bonnafé,Michel Treilhou,Jérôme Leprince,Billy K C ChowPubMed 34111449
- PloS one 15:e02280152020Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYohei Ando et. al.PubMed 31999765
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35:396-4122019Extracellular Vesicles From Osteotropic Breast Cancer Cells Affect Bone Resident Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexander Loftus,Alfredo Cappariello,Christopher George,Argia Ucci,Kirsty Shefferd,Alice Green,Riccardo Paone,Marco Ponzetti,Simona Delle Monache,Maurizio Muraca,Anna Teti,Nadia RucciPubMed 31610048
- Pharmacological research 144:377-3892019Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJoost Boeckmans et. al.PubMed 31028903
Key facts
- Assay type
Semi-quantitative
- Reactive species
Human
- Target
AGRP
(See target data below)
Target data
Function
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Targets
AREG, ANG, ANGPT2, AXL, BDNF, BTC, NGF, FGF2, CXCL13, BMP4, BMP6, CCL28, CCL23, CNTF, CCL27, CXCL5, EGF, EGFR, CCL11, CCL24, CCL26, FAS, FGF4, FGF6, FGF7, FGF9, FLT3LG, CX3CL1, CXCL6, CSF3, GDNF, TNFRSF18, TNFSF18, CSF2, IL6ST, CXCL1, CXCL3, CCL16, HGF, CCL1, ICAM1, ICAM3, IFNG, IGF1, IGF1R, IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP6, IL1A, IL1B, IL1R1, IL1RL1, IL1RN, IL10, IL11, IL12B, IL12A, IL13, IL15, IL16, IL17A, IL2, IL2RA, IL3, IL4, IL5, IL6, IL6R, IL7, CXCL8, CXCL11, LEP, TNFSF14, XCL1_HUMAN, CCL2, CCL8, CCL7, CCL13, CSF1, CCL22, MIF, CXCL9, CCL3, CCL4, CCL15, CCL20, CCL19, CCL23, MST1, PPBP, NTF3, NTF4, OSM, TNFRSF11B, CCL18, PDGFB, PGF, CCL5, KITLG, CXCL12, CCL17, CCL25, TGFB1, TGFB3, THPO, TIMP1, TIMP2, TNF, LTA, TNFRSF1A, TNFRSF1B, TNFRSF10C, TNFRSF10D, PLAUR, VEGFA, VEGFD
Alternative names
Agouti-related protein, AGRT, ART, AGRP
What's included?
Recommended products
ab193656 can be used for the simultaneous detection of 120 Human Cytokine proteins in serum, plasma, cell culture media and other liquid samples types.
Key facts
- Assay type
Semi-quantitative
- Reactive species
Human
- Target
AGRP
- Applications
Multiplex Protein Detection
- Detection method
Luminescent
- Sample types
Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage conditions
-20°C
- Appropriate long-term storage conditions
-20°C
- Storage information
-20°C
Notes
ab193656 can be used for the simultaneous detection of 120 Human Cytokine proteins in serum, plasma, cell culture media and other liquid samples types. It comes as 1 kit including 2 separate membranes labelled C6 and C7 (see below for images showing the array layout on each membrane)."
Targets names: Adiponectin (ACRP30), AgRP, Amphiregulin, Angiogenin, Angiopoietin-2, Axl, BDNF, bFGF, BLC (CXCL13), BMP-4, BMP-6, beta-NGF, Betacellulin (BTC), CCL28 (MEC), CK beta 8-1 (CCL23), CNTF, CTACK (CCL27), Dtk, EGF, EGFR, ENA-78 (CXCL5), Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), Eotaxin-3 (CCL26), Fas,(TNFRSF6/Apo-1), FGF-4, FGF-6, FGF-7 (KGF), FGF-9, Flt-3 Ligand, Fractalkine (CX3CL1), GCP-2 (CXCL6), GCSF, GDNF, GITR (TNFRSF18), GITR Ligand (TNFSF18), GM-CSF, GRO alpha/beta/gamma, GRO alpha (CXCL1), HCC-4 (CCL16), HGF, I-309 (TCA-3/CCL1), CCAM-1 (CD54), ICAM-3 (CD50), IFN-gamma, IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-6, IGF-1, IGF-1 R, IL-1 R4 (ST2), IL-1 R1, IL-10, IL-11, IL-12 p40, IL-12 p70, IL-13, IL-15, IL-16 IL-17A, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-1 ra (IL-1 F3), IL-2, IL-2 R alpha, IL-3, IL-4, IL-5, IL-6, IL-6 R, IL-7, IL-8 (CXCL8), I-TAC (CXCL11), Leptin Light (TNFSF14), Lymphotactin (XCL1), MCP-1 (CCL2), MCP-2 (CCL8), MCP-3 (MARC/CCL7), MCP-4 (CCL13), M-CSF, MDC (CCL22), MIF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 beta (CCL4), MIP-1 delta (CCL15), MIP-3 alpha (CCL20), MIP-3 beta (CCL19), MSP alpha/beta, NAP-2 (PPBP/CXCL7), NT-3, NT-4, Oncostatin M, Osteoprotegerin (TNFRSF11B), PARC (CCL18), PDGF-BB, PLGF, RANTES (CCL5), SCF, SDF-1 alpha (CXCL12 alpha), gp130, TNF RII (TNFRSF1B), TNF RI (TNFRSF1A), TARC (CCL17), TECK (CCL25), TGF beta 3, TGF beta 1, Thrombopoietin (TPO), TIMP-1, TIMP-2, TNF alpha, TNF beta (TNFSF1B), TRAIL R3 (TNFRSF10C), TRAIL R4 (TNFRSF10D), uPAR, VEGF-A, VEGF-D.Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
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Multiplex Protein Detection - Human Cytokine Antibody Array - Membrane (120 Targets) (ab193656)
Typical images obtained with Abcam Human Cytokine Antibody Array - Membrane C7 (120 Targets) ab193656. These membranes were probed with conditioned media from two different cell lines. Membranes were exposed to film at room temperature for 1 minute.
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