ab197453 can be used for quantitative measurement of 10 Human MMPs.
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- International journal of molecular sciences 21:2020Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLaura R Moffitt et. al.PubMed 33143089
- Molecular cancer research : MCR 15:1398-14092017p120-Catenin Downregulation and Mutations Cooperate to Induce Invasion through MMP1 in HNSCC.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMichal Kidacki et. al.PubMed 28637905
Key facts
- Assay type
- Quantitative
- Reactive species
- Human
- Target
- MMP1
(See target data below) - Assay Platform
- Multiplex
Target data
Function
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:1645757, PubMed:2153297, PubMed:2557822). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369).
Additional Targets
MMP10, MMP13, MMP2, MMP3, MMP8, TIMP1, TIMP2, Metalloproteinase inhibitor 4
Alternative names
CLG, MMP1, Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1
What's included?
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ab197453 can be used for quantitative measurement of 10 Human MMPs.
Key facts
- Assay type
- Quantitative
- Reactive species
- Human
- Target
- MMP1
- Detection method
- Fluorescent
- Assay Platform
- Multiplex
- Sample types
- Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- -20°C
Notes
ab197453 can be used for quantitative measurement of 10 Human MMPs. Suitable for serum, plasma, cell culture media, other body fluids, cell and tissue lysates.
Target names: MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-10, MMP-13, TIMP-1, TIMP-2, TIMP-4.
Quantitative antibody arrays can be used to quantitate up to 40 cytokines with as little as 50 µL of sample. Arrays are available for 400 human and 200 mouse proteins. Each glass slide is spotted with 16 identical antibody arrays and is provided with a 16 well gasket to allow separate samples to be applied to each array. Each antibody is spotted in quadruplicate in each array. For reproducible quantitation, eight of the arrays are used with a cocktail of protein standards to produce a standard curve. The same 8 standard curve arrays can be used across multiple slides, allowing measurement of 22 experimental samples with 2 slides, 36 with 3 slides etc. For high through-put, 4 slides can be nested into a tray matching a standard microplate, allowing automated processing with a liquid handling workstation. Array processing can be completed within one working day (see workflow diagram below) and arrays can be analyzed with a wide number of laser glass slide array / gene microarray scanners. If you don’t have a suitable scanner then we recommend our membrane antibody arrays, which can be analyzed with any WB chemiluminescent reader. The standard is affinity purified. "
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2 product images
Multiplex Protein Detection - Human MMP Antibody Array (10 Targets) - Quantitative (ab197453)
Array Map for Human MMP Antibody Array (10 Targets) - Quantitative (ab197453).
Multiplex Protein Detection - Human MMP Antibody Array (10 Targets) - Quantitative (ab197453)
Standard Curves obtained with Abcam Human MMP Antibody Array (10 Targets) - Quantitative (ab197453).
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